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Common methods for fabrication of polyelectrolyte microcapsules rely on a multi-step process. We propose a single-step approach to generate polyelectrolyte microcapsules with 1-2 μm shells based on polyelectrolyte complexation across a water/oil droplet interface and study the effect of parameters controlling the polyelectrolyte complexation on shell thickness.
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http://dx.doi.org/10.1039/c4lc00482e | DOI Listing |
Int J Biol Macromol
August 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China. Electronic address:
The rapid digestion of starch can cause blood sugar spikes, contributing to health issues like diabetes. Encapsulating starch to control its digestibility is a promising strategy in functional food development. A hierarchical core-shell microarchitecture was designed through sequential encapsulation, co-encapsulating oat starch and protein within a nutrient-dense core, followed by the assembly of tunable polysaccharide shells.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Kurchatov Complex of Crystallography and Photonics of the National Research Centre "Kurchatov Institute", Moscow 119333, Russia.
Aim: This study establishes the mechanism of stable emulsion capsules formation using sulfhydryl-free polysaccharides (xanthan gum, chitosan, and their mixtures), comparing ultrasonic versus conventional mechanical preparation methods.
Methods: Capsules were fabricated using both mechanical and ultrasonic processing, followed by comprehensive characterization through DLS, CLSM, CRYO electron microscopies, XPS, FTIR, AFM, XRD, and TGA.
Results: Ultrasonically processed xanthan gum/chitosan capsules exhibit a well-defined morphology (1 μm average size), stable surface characteristics (-19 mV zeta potential), and enhanced resistance to aggregation and coalescence.
Polymers (Basel)
August 2025
Institute of Theoretical and Experimental Biophysics Russian Academy of Science, Institutskaya St., 3, 142290 Puschino, Moscow Region, Russia.
The development of layer-by-layer polyelectrolyte microcapsules (PMCs) with defined buffer capacity (BC) is a key task for creating stable systems in biomedicine and materials science. Manganese carbonate (MnCO), which shares properties with CaCO and the ability to form hollow structures, represents a promising alternative. However, its interaction with polyelectrolytes and its influence on BC remain insufficiently studied.
View Article and Find Full Text PDFMater Horiz
July 2025
School of Chemical Engineering and Technology and State Key Laboratory of Chemical Engineering and Low-Carbon Technology, Tianjin University, Tianjin 300350, P. R. China.
Dynamic, responsive microcapsules present innovative solutions for mitigating corrosion and environmental challenges associated with CO capture, utilization, and storage. For their prospective integration into practical applications, these microcapsules must possess structures that optimally balance responsiveness and structural integrity under harsh acidic environments. Here, we report robust pH-responsive microcapsules (RRMCs) that are synthesized using a dynamic complexation-diffusion assembly approach, incorporating polyelectrolytes of varying molecular weights.
View Article and Find Full Text PDFPolymers (Basel)
July 2025
Institute of Theoretical and Experimental Biophysics Russian Academy of Science, Institutskaya St., 3, Puschino 142290, Moscow Region, Russia.
The encapsulation of hydrophobic substances remains a significant challenge due to limitations such as low loading efficiency, leakage, and poor distribution within microcapsules. This study introduces a novel strategy utilizing colloidosomes assembled from polyelectrolyte microcapsules (PMCs). PMCs were fabricated via layer-by-layer (LbL) assembly on manganese carbonate (MnCO) or calcium carbonate (CaCO) cores, followed by core dissolution.
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