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Changes in food choices and dietary patterns during the lifestyle intervention and their association with type 2 diabetes risk in participants with high or low genetic risk for type 2 diabetes.
Eur J Nutr
September 2025
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, PO Box 1627, 70211, Kuopio, Finland.
Purpose: To investigate how a group-based lifestyle intervention affects food choices and if the dietary patterns at the end of the intervention are associated with incidence type 2 diabetes (T2D). We also investigated if the possible associations between diet and T2D risk were modified by the genetic risk for T2D.
Methods: Participants in the T2D-GENE study were men with prediabetes aged 50-75 years, body mass index ≥ 25 kg/m, belonging in either low or high genetic risk score (GRS) tertile for T2D.
Modifying the highland barley gliadin with reducing sugar grafting and enhancing its structural and functional properties.
Int J Biol Macromol
September 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, 712100, PR China. Electronic address:
As the primary storage protein, highland barley gliadin (HBG) exhibits limitations in the processing of highland barley foods, primarily due to its abundant non-polar amino acids. In this study, HBG was utilized to prepare sugar-HBG complexes with pentose (xylose), hexoses (glucose and galactose), and disaccharides (lactose and maltose) in an aqueous system at a pH of 11 and a temperature of 75 °C. Subsequently, the structural and functional characteristics of these complexes were evaluated.
View Article and Find Full Text PDFAssociation of METS-IR with Pregnancy Outcomes in Euthyroid Women: A Retrospective Cohort Study.
Horm Metab Res
September 2025
Department of Obstetrics, Fujian Maternity and Child Health Hospital, Fuzhou, China.
The non-insulin-based metabolic score for insulin resistance (METS-IR) is a recently developed index aimed at being a practical and efficient alternative biomarker of insulin resistance (IR). This study aimed to investigate the association between METS-IR in euthyroid women in the first trimester of pregnancy and pregnancy outcomes. A total of 1810 participants who gave birth at Fujian Maternity and Child Health Hospital from November 2018 to November 2019 were included in this study.
View Article and Find Full Text PDFEffects of prolonged unsaturated fatty acid supplementation on reproductive competence and metabolic profiles in serum and follicular fluid of Holstein heifers.
Anim Reprod Sci
September 2025
Department of Animal Production and Animal Nutrition, University of Sao Paulo, Pirassununga 13635-900, Brazil. Electronic address:
This study evaluated the effects of a 120-d dietary supplementation with unsaturated fatty acids from soybean grain and flaxseed on oocyte quality, in vitro embryo quality and production, and the metabolic profiles of blood and follicular fluid in Holstein heifers. Twenty-four heifers were assigned to the following treatments: a control diet (CON) and diets supplemented with whole raw soybeans (WRS) or flaxseed (FLX), both formulated to increase ether extract content to approximately 4.5 % dry matter (DM).
View Article and Find Full Text PDFKey factors underpinning neuroimmune-metabolic-oxidative (NIMETOX) major depression in outpatients: paraoxonase 1 activity, reverse cholesterol transport, increased atherogenicity, protein oxidation, and differently expressed cytokine networks.
Neuro Endocrinol Lett
September 2025
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China.
Background: Major depressive disorder (MDD) is associated with neuro-immune - metabolic - oxidative (NIMETOX) pathways.
Aims: To examine the connections among NIMETOX pathways in outpatient MDD (OMDD) with and without metabolic syndrome (MetS); and to determine the prevalence of NIMETOX aberrations in a cohort of OMDD patients.
Methods: We included 67 healthy controls and 66 OMDD patients and we assessed various NIMETOX pathways.