98%
921
2 minutes
20
Although breast conservation surgery (BCS) is commonly performed, several aspects of the procedure remain controversial. We undertook a cross-sectional survey to compare Canadian (CDN) and American (AM) general surgeons' reported BCS practice patterns to better understand the cross-border differences in early-stage breast cancer surgery care. A modified Dillman Method survey was mailed to 1,447 AM and 1,443 CDN surgeons. Factors evaluated included preoperative assessment, margin definition, surgical techniques, and re-excision practices. The response rate was 26% and 51% for AM and CDN surgeons, respectively. There was variation in use of preoperative core biopsies. American surgeons required wider margins for invasive cancer and ductal carcinoma in situ, and more often recommend re-excision for invasive cancer with 1 and 2 mm margins (p < 0.05). There was also variability in surgical techniques used for intraoperative margin assessment. Wide variation in BCS practice was observed, with some of this variability related to surgeon country.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/tbj.12299 | DOI Listing |
PLoS One
September 2025
School of Social Sciences and Global Studies, The Open University, Milton Keynes, United Kingdom.
Background: There is evidence that cerebral palsy (CP) could be linked to stigma and discrimination, however current evidence is limited to small qualitative studies. The goal of this co-designed survey was to elicit information on experiences of stigma and discrimination amongst a larger sample of adults in the UK and Ireland.
Methods: Quantitative questions about sources of stigma and qualitative questions designed to elicit information on experiences of stigma were shared via an online survey.
Khirurgiia (Mosk)
September 2025
Children's City Clinical Hospital No. 9, named after G.N. Speransky, Moscow, Russia.
Background: The paper addresses an important section of pediatric combustiology - generalized meningococcal infection, associated with a severe course, the risk of disabling complications, life-threatening conditions, and high mortality.
Objective: The purpose of the study was to share the experience of treating patients with the sequelae of generalized bacterial infection caused by in a children's burn center.
Material And Methods: We conducted a retrospective analysis of the medical records of 23 patients treated in the burn department for babies from 0 to 3 years of the Children's City Clinical Hospital No.
Anesthesiology
October 2025
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Despite the widespread use of clinical anesthesia, the process of emergence from general anesthesia remains primarily driven by anesthetic elimination. Although emergence from general anesthesia is typically safe, prolonged delays strain resource-intensive settings and contribute to increased healthcare costs. In addition to improving access to care, providing clinicians with more precise control over emergence could offer diagnostic potential and improve patient outcomes.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
September 2025
Department of Ophthalmology, Edward S. Harkness Eye Institute, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, Columbia University, New York, New York, United States.
Purpose: To characterize a no b-wave (nob) mouse model of congenital stationary night blindness (CSNB) caused by a Grm6 variant that disrupts photoreceptor-to-bipolar cell signaling. Additionally, we aim to evaluate the efficacy of gene therapy in restoring visual function.
Methods: The nob mouse was generated through selective breeding to regenerate the nob phenotype.
JTCVS Open
August 2025
Department of Thoracic Surgery, Hull University Teaching Hospitals, Hull, United Kingdom.
Objective: The underrepresentation of women in thoracic surgery has been well described worldwide. Women can serve as role models for trainees and advance their careers through academic appointments, leadership positions, and involvement in thoracic societies. We aimed to characterize differences between representation of women in thoracic surgery in the United States and Europe.
View Article and Find Full Text PDF