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Article Abstract

Unlabelled: Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO2 ) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials.

Conclusion: SpO2 of 85-89% can increase mortality and 91-95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87-94% or 88-94%, may be safer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225465PMC
http://dx.doi.org/10.1111/apa.12692DOI Listing

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