Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The aim of this study was to investigate the melatonin-mediated effects upon the neuroendocrine axis of the brackish killifish (Fundulus heteroclitus), a suitable experimental model to study reproductive events. The ability of melatonin to enhance reproductive capacity (fecundity, embryo survival and hatching rate) inducing the transcriptional activity of gonadotropin releasing hormone (gnrh), luteinizing hormone receptor (lhr) and melatonin receptor (mtnr) was investigated in adult females. Moreover, the melatonin-mediated enhancement of killifish sperm motility and velocity was found consistent with higher fecundity of melatonin-exposed fishes. As a further extent, Fourier Transform Infrared (FT-IR) microspectroscopy evidenced a reduction of lipid unsaturation level on isolated spermatozoa from treated males. Moreover, the reduction of mtnr gene expression during embryo development and lower biometric parameters documented in the larvae from melatonin-exposed parents suggest that melatonin acts as a hormonal mediator able to transfer the environmental signal to oocytes and then to embryos as inheritance of adaptive environmental changes. These results support the positive role of melatonin on killifish reproduction and its role as a maternal factor on embryo and larval development.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cbpa.2014.02.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evidence for a JA-responsive SNAC1-ASMT1 regulatory module contributing to melatonin-mediated salinity stress tolerance in Barley.
J Plant Physiol
August 2025
Department of Seed and Plant Improvement Research, Fars Agriculture and Natural Resources Research and Education Center, Agricultural Research, Education and Extension Organization (AREEO), Shiraz, Iran.
Melatonin has emerged as a crucial mediator in plant responses to abiotic stresses, with its regulatory effects closely dependent on its endogenous levels and biosynthetic dynamics. However, in barley (Hordeum vulgare L.), the upstream regulatory mechanisms of melatonin biosynthesis under salinity stress, and their connection to hormonal signaling, remain largely unknown.
View Article and Find Full Text PDFAnalysis of the AP2/ERF transcription factor family in Eriobotrya japonica and its role in exogenous melatonin-mediated regulation of salt stress.
Funct Integr Genomics
July 2025
Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, 650224, China.
AP2/ERF transcription factors (TFs) are involved in various regulatory pathways related to plant growth, development, and stress responses. The growth of Eriobotrya japonica, a popular fruit and medicinal plant, is affected by salt stress. Currently, the functions of E.
View Article and Find Full Text PDFMelatonin Mediates Methylglyoxal Homeostasis and Autophagy During Seed Germination Under Polyethylene Glycol-Induced Drought Stress in Upland Cotton.
Physiol Plant
July 2025
Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Methylglyoxal (MGO), a toxic byproduct of glycolysis, acts as a signaling molecule at low levels, but its overaccumulation during drought stress disrupts redox balance and accelerates cell death in plants. Contrarily, melatonin maintains redox balance, particularly during stress. The redox status and MGO levels might differ in drought-sensitive and drought-tolerant varieties, so shall the melatonin's effect.
View Article and Find Full Text PDFIntegrated Physiological and Transcriptomic Analysis Reveals Transcription Factors Are Crucial for Melatonin-Mediated Drought Tolerance in E. ulmoides.
Physiol Plant
July 2025
Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), Institute of Agro-Bioengineering, College of Life Sciences, Guizhou University, Guiyang, Guizhou Province, China.
Eucommia ulmoides is a Chinese herbal medicine, and much attention has been paid to its tolerance mechanism under stress conditions. Among them, drought is a severe stress that affects the plant's growth and development. Here, we assessed the protective efficiency of different concentrations of melatonin in the leaves of Eucommia ulmoides under drought stress.
View Article and Find Full Text PDFTherapeutic insights and molecular mechanism linking melatonin signaling and membranous nephropathy (Review).
Biomed Rep
August 2025
Division of Nephrology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Endogenous melatonin is synthesized at night by specific enzymes and exerts various physiological effects through both melatonin receptor-dependent and -independent pathways. Moreover, exogenous melatonin has been demonstrated to have pleiotropic therapeutic effects on a range of pathological conditions, including renal diseases. The melatonin signaling pathway involves specific enzymes responsible for melatonin synthesis and cellular responses mediated by melatonin, which are evolutionarily conserved in both brain and peripheral tissues.
View Article and Find Full Text PDF