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A comparison has been done between the two cases when intraband effects are included and when they are excluded in the semiconductor optical amplifier model for propagating short pulses. The numerical investigation shows that the dependence of output pulse chirping and broadening on the amplifier gain, input pulse energy, and input pulsewidth becomes stronger on inclusion of intraband effects. To prove the experimental fact of pulsewidth dependency of the amplifier saturated gain for short pulses, it is compulsory to include intraband effects in the model. We prescribe here an expression for the saturation energy as a function of pulsewidth that correctly predicts the variation obtained numerically.
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http://dx.doi.org/10.1364/AO.52.007171 | DOI Listing |
Traffic Inj Prev
September 2025
Chongqing Jianzhu College, Chongqing, P.R. China.
Purpose: The monotonous lighting environment in extra-long tunnels often induces mind-wandering in drivers. To address this issue, this study explores effective strategies to optimize tunnel lighting environments by configuring various background colors and special lighting zones to enhance the alertness of young drivers and ensure driving safety.
Methods: A virtual driving simulator was utilized to carry out the experiment.
J Appl Physiol (1985)
September 2025
Women's Heart Health Laboratory, Institute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, TX, USA.
We investigated the impact of short-term dietary nitrate supplementation on sympathetic neural responses to isometric exercise in postmenopausal women. Ten healthy women aged 64±2 (SD) years participated in this randomized, placebo-controlled, double-blind, crossover study. All participants underwent two-week beetroot juice (BRJ: 800 mg nitrate/day) and placebo (nitrate-depleted BRJ) interventions with ≥14 days of wash-out.
View Article and Find Full Text PDFTissue Eng Part A
September 2025
Department of Chemical and Materials Engineering, Faculty of Engineering, The University of Auckland, Auckland, New Zealand.
Spatially and temporally controlled drug delivery is an important field to address the limitations of conventional pharmaceutical administration. While many effective controlled drug delivery systems exist, the repertoire of systems that additionally present a beneficial mechanical environment to cells remains scarce. To address this, a comprehensive release study of fluorescein as a model drug, and the corticosteroid dexamethasone, from poly(-isopropylacrylamide)/polypyrrole (pNIPAM/PPy) conducting polymer hydrogels is presented within this study.
View Article and Find Full Text PDFDrug Dev Ind Pharm
September 2025
Jiangsu Medical College, Yancheng, 224005, China.
Objective: To prepare astragaloside IV dripping pills (ASDP) and assess their therapeutic effects on mice with doxorubicin hydrochloride-induced dilated cardiomyopathy (DCM).: Astragaloside IV (AS) exhibits pharmacological effects in treating cardiovascular diseases, however, its clinical application is hindered by poor solubility and low bioavailability. The study sheds light on new therapeutic strategy of DCM and development of AS formulations.
View Article and Find Full Text PDFCardiol Rev
September 2025
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Sepsis remains a leading cause of critical illness and mortality worldwide, driven by a dysregulated host response to infection and often complicated by persistent tachycardia and cardiovascular dysfunction. Increasing evidence implicates excessive sympathetic activation as a contributor to sepsis-related hemodynamic instability and myocardial injury, prompting growing interest in the use of β-adrenergic blockade as a therapeutic adjunct. This review synthesizes current data on the safety and efficacy of short-acting, cardioselective β-blockers (BBs), particularly esmolol and landiolol, in septic shock.
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