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In any generally covariant theory of gravity, we show the relationship between the linearized asymptotically conserved current and its nonlinear completion through the identically conserved current. Our formulation for conserved charges is based on the Lagrangian description, and so completely covariant. By using this result, we give a prescription to define quasilocal conserved charges in any higher derivative gravity. As applications of our approach, we demonstrate the angular momentum invariance along the radial direction of black holes and reproduce more efficiently the linearized potential on the asymptotic anti-de Sitter space.
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http://dx.doi.org/10.1103/PhysRevLett.111.081101 | DOI Listing |
Langmuir
September 2025
College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, PR China.
Sodium-ion batteries are promising candidates for large-scale energy storage due to their low cost and resource abundance. However, their cathode materials suffer from poor conductivity and limited cycling stability. Here, we report a Prussian blue (PB)-based cathode hybridized with carboxyl-functionalized carbon nanotubes (CNTs) via a glutamic acid-assisted in situ coordination route.
View Article and Find Full Text PDFProtein Pept Lett
September 2025
Center for Advanced Therapeutics, Institute of Molecular Biosciences, Mahidol University, Salaya Campus, Nakornpathom 73170, Thailand.
Background: Bacillus thuringiensis Cry toxins are well known for their insecticidal properties, primarily through the formation of ion-leakage pores via α4-α5 hairpins. His178 in helix 4 of the Cry4Aa mosquito-active toxin has been suggested to play a crucial role in its biotoxicity.
Objective: This study aimed to investigate the functional importance of Cry4Aa-His178 through experimental and computational analyses.
J Phys Chem B
September 2025
Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.
HMGB1, a nuclear DNA-binding protein, can be secreted by activated immune cells or passively released from damaged cells. In such cases, HMGB1 functions as an alarmin that activates the immune system. Excessive inflammation may lead to pathogenesis, whereas this response can be dampened by polyanion binding, which impedes further receptor recognition.
View Article and Find Full Text PDFThe T138R mutation in Aquaporin 0 (AQP0), a key membrane protein in the ocular lens, causes autosomal dominant congenital cataracts. Whilst previous studies have demonstrated that this mutation disrupts water permeability and leads to protein mislocalisation, the specific structural mechanisms underlying these functional defects remain unclear. This study employed in silico approaches to characterise how the T138R substitution affects AQP0's molecular structure and stability.
View Article and Find Full Text PDFMagn Reson Chem
September 2025
Transcription Regulation Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
Epithelial splicing regulatory protein 2 (ESRP2) plays a pivotal role in alternative splicing regulation, particularly in maintaining epithelial cell identity and suppressing epithelial-to-mesenchymal transition (EMT). Despite its biological significance, the structural basis for its RNA-binding specificity remains poorly understood. In this study, we report the solution structure and RNA-binding properties of the RNA Recognition Motif (RRM3) of human ESRP2 using an integrative approach combining nuclear magnetic resonance (NMR) spectroscopy, ITC, molecular docking, and MD simulations.
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