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Structural features, synthesis, and reactivity of Zn-biphenyl metal-organic frameworks with MOF-5 topology are presented to show the chemical flexibility of such materials and to demonstrate the challenges that can be encountered and solved to avoid interpenetration. We introduce the synthesis of a Zn-biphenyl MOF with diphenylphosphino functionalization and illustrate its structural and chemical properties.
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http://dx.doi.org/10.2533/chimia.2013.397 | DOI Listing |
J Am Chem Soc
September 2025
Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Once physical organic curiosities, bicyclo[2.1.0]pentanes (colloquially termed housanes) are useful strain-release reagents and are unique structural motifs for medicinal chemistry campaigns because of their high Fsp content.
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September 2025
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Background: Maternal childhood maltreatment has been associated with higher risk of adverse neurodevelopment in offspring. Chronic systemic inflammation has been associated with childhood maltreatment and has been identified as a gestational risk factor for adverse neurodevelopment in offspring. Thus, inflammation may be a mechanism by which maternal exposure to maltreatment affects offspring neurodevelopment.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Background: Antimicrobial resistance is a globally recognised public health threat. In rural China, antibiotic use is common for acute respiratory infections (ARIs), which include symptoms such as coughing and fever that are most likely viral infections but with a small proportion as bacterial infections. This study aims to evaluate the effectiveness of a comprehensive intervention based on C-reactive protein and serum amyloid A point-of-care testing (CRP&SAA POCT) in reducing the inappropriate use of antibiotics for ARIs in Chinese village clinics.
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September 2025
Laboratory of Molecular and Cellular Immunology, Institute of Molecular Biology, National Academy of Sciences, Yerevan, Armenia.
The short lifespan of polymorphonuclear neutrophils (PMNs) in vitro poses challenges, as their limited viability restricts functional assays and experimental manipulations. The HL-60 cell line serves as a valuable model for neutrophil-like differentiation, yet the functional relevance of ATRA- and DMSO-induced differentiation remains incompletely understood. In the present study, we aimed to characterize the differentiation potential of all-trans retinoic acid (ATRA) and dimethyl sulfoxide (DMSO) on HL-60 cells and compare their functionality with primary PMNs.
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September 2025
Department of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, United States of America.
Nitrogen (N) fixation with non-thermal plasmas has been proposed as a sustainable alternative to meet growing N fertilizer demands for agriculture. This technology generates Plasma Activated Water (PAW) with a range of chemical compositions, including different concentrations of nitrate (NO₃⁻) and hydrogen peroxide (H2O2), among other compounds. Potential use of PAW as an effective crop fertilizer necessitates a robust understanding of the underlying biology of the plant, which is not yet available.
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