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A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR.
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http://dx.doi.org/10.1080/10286020.2012.743529 | DOI Listing |
Phytochemistry
June 2025
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Nankai International Advanced Research Institute (Shenzhen Futian), Nankai University, Tianjin, 300353, People's Republic of China. Electronic address:
Nine previously undescribed polyoxygenated cyclohexenes uvacalols L-T (1-9), together with five known analogues (10-14) were obtained from the stems of Uvaria calamistrata. Their structures were established through spectroscopic data analysis, circular dichroism calculations and single-crystal X-ray diffraction. Uvacalols L-N (1-3) are chlorinated analogues.
View Article and Find Full Text PDFSci Rep
June 2024
Program in Chemical Sciences, Chulabhorn Graduate Institute, Bangkok, Thailand.
Twelve polyoxygenated cyclohex(a/e)ne diterpene esters, named albiflorenes A-L (1-12), were isolated from the whole plants of Kaempferia albiflora, known as "Prao Mang Mum." Their structures and relative stereochemistry were determined by extensive spectroscopic analysis. Furthermore, the comparison of experimental electronic circular dichroism (ECD) curves with the curves predicted by TDDFT was used to determine the absolute configurations.
View Article and Find Full Text PDFFitoterapia
June 2024
Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam. Electronic address:
A phytochemical study of the aerial parts of Piper mutabile C. DC. revealed seven undescribed compounds [two (2-7')-neolignans and five polyoxygenated cyclohexene glycosides] and six known propenylcatechol derivatives.
View Article and Find Full Text PDFFront Pharmacol
January 2024
Department of Neurosurgery, Shenzhen Second People's Hospital/The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.
Due to its highly aggressiveness and malignancy, glioblastoma (GBM) urgently requires a safe and effective treatment strategy. Zeylenone, a natural polyoxygenated cyclohexenes compound isolated from , has exhibited potential biological activities in various human diseases, including tumors. We designed and synthesized a series of (+)-Zeylenone analogues and evaluated their anti-GBM roles through structural-activity analysis.
View Article and Find Full Text PDFNat Prod Res
December 2024
Chemistry Department, University of Dar es Salaam, Dar es Salaam, Tanzania.
This article reviews the geographical distribution, ethnomedicinal applications, and phytochemistry of the genus Baill, tribe Uvariae of the family Annonaceae. The reviewed works of literature were collected from various electronic databases including Google Scholar, PubMed, Science Direct, The International Plant Names Index (IPNI), and Research Gate. During this review, ninety-eight species of the genus were found to be widely distributed in tropical Africa.
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