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According to the requirements of rapid detection of important life parameters for the sick and wounded, a new micro bio-chemical detection configuration was proposed utilizing continuous spectroscopy analysis, which was founded on MOEMS and embedded technology. The configuration was developed as so much research work was carried out on the detecting objects and methods. Important parameters such as stray light, absorbance linearity, absorbance ratability, stability and temperature accuracy of the instrument were tested, which are all in good agreement with the design requirements. Clinic tests show that it can detect multiple life parameters quickly (Na+, GLU, Hb eg.).
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Front Vet Sci
August 2025
Department of Musculoskeletal Biology and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.
Body composition metrics such as bodyweight, body condition score (BCS) and muscle condition score (MCS) can be readily recorded as part of veterinary examinations in ageing cats. However, the description of how these parameters change with age, whilst accounting for sex and age-related morbidity, is limited. The aim of this prospective cohort study was to evaluate age, sex and health-related changes in bodyweight, BCS and MCS in client-owned pet cats.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, 1090 Brussels, Belgium.
Despite continued advancements in transcatheter aortic valve implantation (TAVI) techniques, the incidence of permanent pacemaker implantation (PPI) remains substantial. Established predictors of PPI include advanced age, pre-existing electrocardiographic conduction abnormalities, prosthetic valve type, implantation depth, and anatomical parameters, such as membranous septum length, which are currently under active investigation. In routine clinical practice, the management strategy often involves the temporary placement of a transvenous pacemaker lead, followed by a period of observation.
View Article and Find Full Text PDFChem Sci
August 2025
Graduate School of Pharmaceutical Sciences, The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo 113-0033 Japan.
Residence time, which refers to the average duration a drug remains bound to its receptor, is a crucial parameter in determining its pharmacological effects. However, the mechanisms governing the residence time of G protein-coupled receptor (GPCR) ligands remain unclear. In this study, we observed NMR signals from the methyl groups of alanine and methionine located at the intersection of the binding cavity and extracellular loops of AAR under conditions where E165Q and T256A mutations led to reduced residence times.
View Article and Find Full Text PDFVet World
July 2025
Research Center for Horticulture, National Research and Innovation Agency, Jl. Raya Jakarta-Bogor No.32, Pakansari, Kec. Cibinong, Kabupaten Bogor, West Java 16915, Indonesia.
Background And Aim: Purple sweet potatoes ( var. Ayamurasaki) possess high nutritional potential due to their rich content of amino acids, minerals, and fatty acids. However, their nutritional profile can be further improved through fermentation.
View Article and Find Full Text PDFVet World
July 2025
Latvia University of Life Sciences and Technologies, Faculty of Veterinary Medicine, Clinical Institute, Jelgava, LV-3004, Latvia.
Background And Aim: Gastrointestinal nematode infections have a significant impact on the health and productivity of sheep worldwide. Conventional anthelmintics are facing rising resistance, prompting the need for alternative control strategies. (tansy), a traditionally used antiparasitic herb in Latvia, has shown efficacy but lacks delivery validation.
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