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Some listeners are insensitive to the direction of pure-tone frequency changes when the standard frequency is roved widely over trials, but less so when the standard frequency is fixed and trial-by-trial feedback is provided. The present experiment tested the hypothesis that fixing the standard frequency and providing feedback is advantageous for direction-impaired listeners because under these conditions the listeners can learn to respond correctly without genuinely perceiving frequency-change direction. This hypothesis was ruled out by the experiment. It appears instead that direction-impaired listeners find it difficult to ignore the irrelevant frequency changes introduced by roving.
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http://dx.doi.org/10.1121/1.3629139 | DOI Listing |
J Am Assoc Lab Anim Sci
March 2025
Animal Resources Center, Department of Surgery, University of Chicago, Chicago, Illinois; and.
The Guide for the Care and Use of Laboratory Animals provides recommendations on sanitation frequencies for rodent caging equipment; however, it allows for performance standards to be used when extending this frequency for individually ventilated cage (IVC) caging. Our institution wanted to reexamine our current standards of care for mouse IVC caging, which includes a 14-d cage bottom and bedding change as well as the use of corncob bedding. This was driven by desire to reduce the stress to mice associated with cage change, and by recent literature showing a potential improved absorbency and multiple health and welfare benefits of paper pulp cellulose bedding products.
View Article and Find Full Text PDFFASEB J
September 2025
Intensive Care Unit, Dongguan Traditional Chinese Medicine Hospital, Dongguan, Guangdong Province, China.
This study aimed to evaluate the quality of multidisciplinary team (MDT) management in healthcare-associated infection (HAI) prevention and control, as well as its impact on multidrug-resistant organism (MDRO) infections. This was a retrospective, single-center study with a small sample size. A total of 400 patients admitted to the Departments of Critical Care Medicine or Orthopedics between January 2022 and December 2023 were divided into a control group (n = 200, receiving conventional HAI management) and an experimental group (n = 200, undergoing MDT management).
View Article and Find Full Text PDFAging Cell
September 2025
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, USA.
Entropy, characterized by increased disorder throughout biological systems, can be quantified by homeostatic dysregulation (HD). One potential measure of HD is the dispersion of points from a normal value, approximated at the individual level by Mahalanobis distance (D). We hypothesized that greater HD in electrocardiogram (ECG) would also reflect greater HD in the musculoskeletal system which, in turn, would be associated with age and manifest as an increased risk of fracture independently of age, bone mineral density (BMD), and history of fracture.
View Article and Find Full Text PDFJDR Clin Trans Res
September 2025
School of Dentistry, Faculty of Health and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Objectives: Socioeconomic status (SES) has a significant effect on the burden of early childhood caries (ECC), yet addressing SES disparities remains challenging. This study aimed to identify and quantify the most impactful mediator linking SES effect to the occurrence of ECC using advanced causal mediation analysis, to inform targeted interventions that reduce SES-related disparities in ECC.
Methods: Data were drawn from the Study of Mothers' and Infants' Life Events, a cohort of 2,182 mother-child dyads recruited from Adelaide's 3 largest public hospitals (2013-2014).
J Vet Intern Med
September 2025
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.
Background: Echocardiographic reference intervals for Quarter Horses are infrequently reported.
Objectives: To provide standard echocardiographic measurements for sedentary Quarter Horses and evaluate the relationship between physical characteristics (body weight, age, sex) and echocardiographic measurements.
Animals: Forty-one sedentary Quarter Horses, free of cardiac disease, from a university research herd.