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Objective: To provide references for forensic expertise by investigating the kinds of toxicant, routes of exposure and manners of poisoning deaths, etc.
Methods: Six hundred and seven autopsy cases of poisoning deaths from 1957 to 2008 in Department of Forensic Medicine, Tongji Medical College (Tongji Forensic Science Identification Center of Hubei), were comparatively reviewed.
Results: In 218 cases from 1999 to 2008, more than 50% of decedents were male in the ages of 30-49. The toxicants are usually taken orally and the most common manner of death was accidental. The common substances involved in poisoning death were rodenticide, poisoning gas and insecticide. Compared to the data of 1983-1998 and 1957-1982, the common toxic agents had changed significantly. The number of cases involving insecticide and cyanide poisoning decreased in recent years, and the number of cases of rodenticide, poisoning gas, alcohols poisoning displayed an increase tendency, especially for drugs abuse.
Conclusion: Poisoning deaths of pesticides remain a major public health problem for a long time and the awareness of prevention need to be raised, especially for the prevention of deaths from multiple poisons.
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Ann Med
December 2025
Faculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Balıkesir University, Balıkesir, Turkey.
Introduction: Injuries sustained by animals are now common. A review of cases shows that injuries usually manifest as penetrating injuries, lacerations, crushing and tissue rupture. These can lead to severe complications, including infection, deformity, zoonotic diseases and, in extreme cases, death.
View Article and Find Full Text PDFClin Toxicol (Phila)
August 2025
Department of Emergency Medicine, Oregon Health & Science University, Portland, OR, USA.
Introduction: Amlodipine, a dihydropyridine calcium channel blocker, is a growing cause of poisoning fatalities in the United States. As it takes several hours following ingestion for amlodipine peak plasma concentrations to be reached, the severity of poisoning may not be immediately apparent to clinicians. This study aimed to stratify reported amlodipine exposure doses with the severity of clinical outcomes.
View Article and Find Full Text PDFToxicology
September 2025
French Armed Forces Biomedical Research Institute, CBRN defense Division, Toxicology and Chemical Risks Department, France.
The chemical risk associated with the use of organophosphorus nerve agents remains a major concern, as highlighted by recent international events (e.g., Syrian conflict, Novichok poisoning incidents) and the tense geopolitical climate.
View Article and Find Full Text PDFLakartidningen
September 2025
med dr, överläkare, Giftinformationscentralen.
In 2019 the Swedish Poisons Information Centre (SPIC) was contacted in 1 198 hospital cases of intentional poisonings with antidepressants. Severe poisonings identified using the Poison Severity Score were divided by the number of prescriptions for the respective antidepressant per 1 000 inhabitants, yielding a substance specific poisoning severity index (PSI). Amitriptyline, clomipramine, venlafaxine and bupropion had PSIs surpassing all other antidepressants by nearly an order of magnitude and comprised almost 80% of 101 serious poisonings.
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