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Several studies have linked increases in the N2 and P3 components to response conflict, evoked when multiple incompatible responses are simultaneously activated. However, these studies confound a change of response with a change of stimulus identity, and often a change in stimulus probability also. In two experiments, additional trial types were presented, which signified a change of stimulus, but still demanded the expected response. RT costs were observed when participants changed a planned response to a different one, and when they activated an unplanned response, but RT was not substantially increased for stimulus mismatch trials when these were clearly linked to the required response. N2 results were mixed and did not clearly favour a stimulus mismatch or response conflict interpretation. For the P3 component, stimulus-related differences were small but significant, with large increases in positivity when participants cancelled the planned response. Further experiments are required to determine the relative contribution of stimulus- and response-related conflict to N2.
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http://dx.doi.org/10.1016/j.ijpsycho.2011.07.019 | DOI Listing |
ACS Nano
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan 523808, China.
Mimicking human brain functionalities with neuromorphic devices represents a pivotal breakthrough in developing bioinspired electronic systems. The human somatosensory system provides critical environmental information and facilitates responses to harmful stimuli, endowing us with good adaptive capabilities. However, current sensing technologies often struggle with insufficient sensitivity, dynamic response, and integration challenges.
View Article and Find Full Text PDFCell Biochem Biophys
September 2025
Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul, 34003, Türkiye, Turkey.
Vitamin B12 is a vital water-soluble vitamin containing a central cobalt atom within its corrin ring structure. It exists in several derivatives, among which methylcobalamin (MeCbl) and adenosylcobalamin (AdCbl) are the biologically active forms that serve as cofactors in essential enzymatic reactions. Although the neurological and hematological consequences of vitamin B12 deficiency have been extensively studied, its role in immune regulation remains less well understood.
View Article and Find Full Text PDFBrain Behav
September 2025
Department of Physical Therapy, Niigata University of Health and Welfare, Niigata, Japan.
Introduction: We aimed to clarify the effects of an active touch intervention using different textures on corticospinal excitability.
Methods: A total of 30 healthy individuals participated in the active touch intervention. Two tactile stimuli were used for intervention: smooth (silk) and rough (hessian) stimuli.
Front Plant Sci
August 2025
Department of Botany, University of Wisconsin-Madison, Madison, WI, United States.
Introduction: The local perception of a stimulus such as wounding can trigger plant-wide responses through the propagation of systemic signals including the vascular transport of diverse chemical messengers, the propagation of electrical changes, and even potentially hydraulic waves that rapidly spread throughout the plant body. These systemic signals trigger changes in second messengers such as Ca2+ that then play roles in triggering subsequent molecular responses. Although the glutamate receptor-like (GLR) channels GLR3.
View Article and Find Full Text PDFJ Magn Reson Imaging
September 2025
Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
Background: Cerebrovascular reactivity reflects changes in cerebral blood flow in response to an acute stimulus and is reflective of the brain's ability to match blood flow to demand. Functional MRI with a breath-hold task can be used to elicit this vasoactive response, but data validity hinges on subject compliance. Determining breath-hold compliance often requires external monitoring equipment.
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