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http://dx.doi.org/10.1002/anie.201101148 | DOI Listing |
Small
May 2025
Department of Chemistry, Seoul National University, Seoul, 08826, Republic of Korea.
Neural interfacing technologies, combined with biospecific targeting and neuroelectrochemical analysis, provide a powerful platform for advancing the understanding of neural communication at the single-cell level. A key factor in this integration is the role of protein-mediated cell adhesion at the cell-electrode interface, which can influence cellular processes such as exocytosis. However, the specific impact of this interaction remains largely unexplored.
View Article and Find Full Text PDFNeuropharmacology
June 2025
Behavioral Neuroscience Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, DHHS, Baltimore, MD, 21224, USA. Electronic address:
This study used oxygen sensors coupled with amperometry to examine changes in brain (nucleus accumbens) and peripheral (subcutaneous space) oxygen levels following intravenous (IV) and intraperitoneal (IP) fentanyl injections at different doses. To avoid stress associated with traditional IP injection, fentanyl was delivered via chronically implanted IP catheter. SC oxygen levels decreased in a dose-dependent monophasic manner, whereas brain oxygen responses were more complex, showing modest increases at low fentanyl doses (<3 μg/kg for IV and <10 μg/kg for IP) and biphasic effects (decrease followed by increase) at higher doses (≥10 μg/kg for IV and ≥270 μg/kg for IP).
View Article and Find Full Text PDFTalanta
March 2025
Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland; Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089, Warsaw, Poland. Electronic address:
The presented study focused on developing and optimizing a modern electroanalytical platform for the direct quantitative determination of galantamine. This work used different voltammetric methods to use a screen-printed sensor with a working boron-doped diamond electrode (SP/BDDE). Beneficial analytical performance for detecting galantamine was achieved in a Britton-Robinson buffer with pH 3.
View Article and Find Full Text PDFAm J Physiol Lung Cell Mol Physiol
December 2024
Behavioral Neuroscience Branch, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, DHHS, Baltimore, Maryland, United States.
Nanomaterials (Basel)
August 2024
School of Chips, XJTLU Entrepreneur College (Taicang), Xi'an Jiaotong-Liverpool University, Taicang, Suzhou 215400, China.
A biocompatible, highly sensitive, and enzyme-free glucose electrochemical sensor was developed based on a copper-cysteamine (Cu-Cy)-modified electrode. The catalytically active biocompatible material Cu-Cy was immobilized on the electrode surface by the natural polymer chitosan (CTS). The electrochemical characterization and glucose response of the Cu-Cy/CTS/glassy carbon electrode (GCE) were investigated by electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and constant potential amperometry.
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