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The present study was designed to examine the reliability and validity of the Autism Psychodynamic Evaluation of Changes (APEC) scale, developed to assess the evolution in individuals with autism under treatment. The APEC scale focuses on the key role of impairment in body image construction, which requires cross-modal sensory integration through emotional communication with motor representations. Thus, the body image construction is associated simultaneously with spatial and temporal organization and allows the emergence of self- and others-representations. The use of the APEC scale, with its seven domains (expression of emotion in relationships, eye contact, body image, graphic productions, exploration of space and objects, time perception, and verbal language), underlines the importance in autistic disorder of anxieties related to body and spatial representations, and of impairment in the body ego construction which is closely linked to the emergence of individuation/separation processes. This study was conducted on 73 children and adolescents with autistic disorder. They were recruited in day care facilities where two caregivers independently gave their ratings based on their clinical observation on a daily basis during the same month. Analyses included assessing construct validity through correspondence analyses and inter-rater reliability using kappa coefficients. The APEC scale offers a reliable and validated psychodynamic assessment of interest for professionals (such as child psychiatrists, caregivers, therapists or teachers) and researchers working with children, adolescents and adults with autistic disorder, especially in the follow-up of their evolution. The APEC scale provides an approach at the interface of psychoanalysis and neuroscience, and is also of interest for clinical and developmental psychology. Using the APEC scale in a range of different practical and research settings will foster links between psychoanalytic perspectives and educational training for children with autistic disorder, and will contribute to the dialogue between psychoanalysis, neuroscience and psychology.
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http://dx.doi.org/10.1016/j.jphysparis.2010.10.002 | DOI Listing |
Integr Environ Assess Manag
July 2025
School of Economics, Guangxi University, Nanning, Guangxi, China.
The shift in value chain trade from globalization to regionalization has provided developing countries with opportunities for value chain upgrading and has influenced trade-related embodied carbon emissions. This study uses panel data on trade and carbon emissions between China and 21 Asia-Pacific Economic Cooperation (APEC) economies from 1991 to 2021, applying a fixed-effects model to analyze changes in embodied carbon emissions. The focus is on China, the largest developing country, as it participates in the APEC regional value chain (RVC) in different ways.
View Article and Find Full Text PDFMar Pollut Bull
June 2025
Korea Marine Litter Institute, Our Sea of East Asia Network, #404, 55-9 Jukrim 5-ro, Gwangdo, Tongyeong, Gyeongnam 53014, Republic of Korea. Electronic address:
This study presents a harmonized decision framework to guide APEC economies in designing shoreline marine debris monitoring programs. By reviewing 31 monitoring programs, we identified five core elements of goals/objectives, debris targets, spatial scale, data collection and management practices and developed eleven decision criteria to guide program design, including objectives, debris size, categories, spatial scale, site selection, training, intervals, measurements, quality control, database management, and data analysis. The study emphasizes tailoring programs to local contexts while ensuring global comparability.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, 410082, Changsha, Hunan, P. R. China.
Immune checkpoint blockade (ICB) therapies have demonstrated remarkable clinical success in treating cancer. However, their objective response rate remains suboptimal because current therapies rely on limited immune checkpoints that fail to cover the multiple immune evasion pathways of cancer. To explore potential ICB strategies, we propose a glycoimmune checkpoint elimination (glycoICE) therapy based on targeted editing of sialoglycans on the tumor cell surface using an aptamer-enzyme chimera (ApEC).
View Article and Find Full Text PDFAnimals (Basel)
September 2024
Institute of Ocean and Earth Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Aquaponics combines aquaculture and hydroponics to offer a sustainable approach to agriculture, addressing food security issues with minimal environmental harm. However, small-scale practitioners face challenges due to a lack of professional knowledge in water chemistry and system maintenance. Economic hurdles, such as operational costs and energy-intensive components, hinder the viability of small-scale aquaponics.
View Article and Find Full Text PDFSoc Psychiatry Psychiatr Epidemiol
May 2025
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 31, Road 3Rd, Bei-Ji-Ge, Dongcheng District, Beijing, 100073, China.
Purpose: Depression is one of the most common mental disorders and substantially decreases socioemotional well-being and health-related quality of life. Analyzing temporal patterns in depressive symptoms can reveal emerging risks that require attention and have implications for mental health promotion. The present study disentangled age, period, and cohort (APC) effects on trends in depressive symptoms and their gender disparities among China's nationally representative samples of middle-aged and older adults.
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