98%
921
2 minutes
20
Cochlear implant (CI) users' spectral resolution is limited by the number of implanted electrodes, interactions between the electrodes, and the underlying neural population. Current steering has been proposed to increase the number of spectral channels beyond the number of physical electrodes, however, electric field interactions may limit CI users' access to current-steered virtual channels (VCs). Current focusing (e.g tripolar stimulation) has been proposed to reduce current spread and thereby reduce interactions. In this study, current steering and current focusing were combined in a four-electrode stimulation pattern, i.e quadrupolar virtual channels (QPVCs). The spread of excitation was measured and compared between QPVC and Monopolar VC (MPVC) stimuli using a forward masking task. Results showed a sharper peak in the excitation pattern and reduced spread of masking for QPVC stimuli. Results from the forward masking study were compared with a previous study measuring VC discrimination ability and showed a weak relationship between spread of excitation and VC discriminability. The results suggest that CI signal processing strategies that utilize both current steering and current focusing might increase CI users' functional spectral resolution by transmitting more channels and reducing channel interactions.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997903 | PMC |
http://dx.doi.org/10.1016/j.heares.2010.09.004 | DOI Listing |
Scand J Psychol
September 2025
School of Psychology, Shanghai Normal University, Shanghai, China.
Promoting intergenerational altruism among the current youth generation is crucial, and belief in a just world (BJW) may be a protective factor for intergenerational altruism. Inspired by the broaden-and-build theory of positive emotion, our research aims to investigate the relationship between BJW and intergenerational altruism among youths as well as to explore the mediating role of subjective well-being and the moderating role of authenticity in the focal relationship. Three empirical sub-studies with cross-sectional, experimental, and longitudinal designs were performed.
View Article and Find Full Text PDFDalton Trans
September 2025
Institute of Low Temperature and Structure Research, Polish Academy of Sciences, 50-422 Wroclaw, Poland.
Inorganic halide perovskites have been the subject of intensive research for their unique properties. Most current research focuses on halide ion exchange to modify the luminescence band gap and optical features. They are obtained mainly in colloids or thin layers, resulting in small grains with a narrow distribution.
View Article and Find Full Text PDFEur J Prev Cardiol
September 2025
Department of Sport, Exercise and Health, Sports and Exercise Medicine, Medical Faculty, University of Basel, Basel, Switzerland.
The current guidelines for cardiovascular disease prevention by the European Society of Cardiology highlight the undisputable benefits of exercise and a physically active lifestyle for cardiovascular risk reduction. In addition to the health benefits of physical activity, observational data suggests that regular physical activity lowers all-cause mortality. However, this was not confirmed by Mendelian randomization studies and randomized controlled trials.
View Article and Find Full Text PDFClinical academics in psychiatry face several inequities, many of which are specific to women academics and intersectional in nature. We characterise the current state of UK academic psychiatry utilising findings of the annual Medical Schools Council clinical academic survey, and consider initiatives seeking to address gaps in supporting the career journeys of women academics.
View Article and Find Full Text PDFMed Sci Monit
August 2025
Independent Laboratory of Translational Medicine, Medical University of Lublin, Lublin, Poland.
Epithelial ovarian cancer (EOC) remains a leading cause of gynecologic cancer mortality, with high rates of recurrence and chemoresistance. Advances in understanding the molecular biology of EOC, particularly BRCA mutations and homologous recombination deficiency (HRD), have led to more targeted therapies. This review provides an updated summary of systemic treatments for EOC, with an emphasis on personalized therapy approaches and emerging therapeutic strategies.
View Article and Find Full Text PDF