Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) often have inflammation and dyslipidemia that accelerate to atherosclerosis. This study aimed to evaluate chronic inflammation and dyslipidemia in CAPD patients.
Methods: We measured inflammatory markers and lipoprotein subclasses in 20 CAPD patients (12 men and 8 women, aged 59.5 ± 9.9 y) and 20 gender-matched controls. Lipoproteins were separated by high-performance liquid chromatography (HPLC) using an anion-exchange column.
Results: High-sensitivity C-reactive protein and serum amyloid A protein (SAA) were higher among CAPD patients vs. controls (1.6 ± 2.2 vs. 0.8 ± 1.2 mg/l, p<0.05; 11.9 ± 12.8 vs. 4.5 ± 2.4 mg/l). HPLC analysis revealed that chylomicron, VLDL, and IDL cholesterol levels were higher among CAPD vs. controls. In contrast, HDL cholesterol was lower among CAPD patients vs. controls. In the subgroup analysis, SAA levels were significantly lower among patients receiving CAPD for >3 y than among controls. However, IDL cholesterol was consistently higher among CAPD patients vs. controls.
Conclusions: CAPD patients have chronic inflammation and dyslipidemia. IDL cholesterol is the only lipoprotein subclass that is consistently elevated regardless of CAPD duration. More attention should be paid to dyslipidemia in the management of the CAPD patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cca.2010.07.016 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Early-Start vs. Late-Start Icodextrin for Children Receiving Chronic Peritoneal Dialysis: Findings from the International Pediatric Peritoneal Dialysis Network.
Clin J Am Soc Nephrol
September 2025
University College London Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.
Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.
Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.
Peritoneal Dialysis in Italy: the 9th GPDP-SIN Census 2024. Twenty Years of Monitoring Peritoneal Dialysis.
G Ital Nefrol
August 2025
Nephrology, Dialysis and Transplantation Unit, ARNAS "Giuseppe Brotzu", Cagliari, Italy.
We report here the results of the 9th National Census (Cs-24) of Peritoneal Dialysis in Italy, carried out in 2025 by the Italian Society of Nephrology's Peritoneal Dialysis Project Group and relating to 2024. The Census was conducted in the 228 non pediatric centers which performed Peritoneal Dialysis (PD) in 2024. The results have been compared with previous Censuses carried out since 2005.
View Article and Find Full Text PDFSimplifying Antibiotic Management of Peritonitis in APD: Evidence from a Non-Inferiority Randomized Trial.
Antibiotics (Basel)
July 2025
Facultad de Medicina, Universidad de Colima, Colima 28040, Mexico.
Introduction/objective: Peritonitis remains a serious complication in patients undergoing automated peritoneal dialysis (APD), requiring prompt and effective antibiotic administration. This study evaluated whether delivering antibiotics directly through APD bags is as effective as administering them via an additional manual daytime exchange.
Methods: We conducted a randomized, single-blind, non-inferiority clinical trial involving patients diagnosed with peritonitis.
A longitudinal study of post-traumatic growth and rumination in patients undergoing continuous ambulatory peritoneal dialysis: A parallel process latent growth curve modelling approach.
J Psychosom Res
August 2025
West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; West China School of Nursing, Sichuan University, Chengdu, Sichuan Province, China. Electronic address:
Objective: To examine the longitudinal trajectories of post-traumatic growth (PTG) and event-related rumination among patients undergoing continuous ambulatory peritoneal dialysis (CAPD), and to explore the dynamic associations between intrusive/deliberate rumination and PTG using a parallel process latent growth curve model.
Methods: A total of 195 CAPD patients were followed over a 12-month period with assessments at four time points (baseline, 2nd, 6th, and 12th month). PTG and rumination were measured using the Chinese versions of the Post-Traumatic Growth Inventory and the Event-Related Rumination Inventory.
Overnight-dwelled amino acid-based peritoneal dialysis solutions for malnutrition in CAPD: a prospective real-world study.
Int Urol Nephrol
August 2025
Department of Nephrology, Gaozhou People's Hospital, Gaozhou, China.
Purpose: To assess the efficacy and safety of amino acid peritoneal dialysis (AA-PD) in improving nutritional status among continuous ambulatory peritoneal dialysis (CAPD) patients with malnutrition in a real-world setting.
Methods: A prospective self-control study was conducted across five hospitals in China. Patients aged 18-75 years with malnutrition [serum albumin < 35 g/L, prealbumin < 300 mg/L, or Subjective Global Assessment (SGA) score > 7] were enrolled.