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During MESSENGER's third flyby of Mercury, the magnetic field in the planet's magnetic tail increased by factors of 2 to 3.5 over intervals of 2 to 3 minutes. Magnetospheric substorms at Earth are powered by similar tail loading, but the amplitude is lower by a factor of approximately 10 and typical durations are approximately 1 hour. The extreme tail loading observed at Mercury implies that the relative intensity of substorms must be much larger than at Earth. The correspondence between the duration of tail field enhancements and the characteristic time for the Dungey cycle, which describes plasma circulation through Mercury's magnetosphere, suggests that such circulation determines the substorm time scale. A key aspect of tail unloading during terrestrial substorms is the acceleration of energetic charged particles, but no acceleration signatures were seen during the MESSENGER flyby.
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http://dx.doi.org/10.1126/science.1188067 | DOI Listing |
Top Magn Reson Imaging
October 2025
BIOSPACE LAB, Nesles-la-Vallée, France.
Aims: Cardiac tumors are aggressive and asymptomatic in early stages, causing late diagnosis and locoregional metastasis. Currently, the standard of care uses gadolinium-based contrast agents for MRI, and the associated hypersensitivity reactions are a significant concern, such as gadolinium deposition disease. In addition, the proximity of cardiac lesions closer to vital structures complicates surgical interventions.
View Article and Find Full Text PDFJ Am Heart Assoc
September 2025
Department of Radiology, Beijing Friendship Hospital Capital Medical University Beijing China.
Background: High blood pressure (BP) is a known risk factor for cognitive decline and dementia, but the underlying mechanisms are largely unknown. We investigated the associations of cumulative BP exposure with hippocampal subfield volume and cognitive function and determined whether hippocampal subfield atrophy mediates the association between cumulative BP exposure and cognitive decline.
Methods: Between December 2020 and March 2023, participants were prospectively included from the Kailuan study.
Trends Biochem Sci
September 2025
Chromatin Dynamics Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Milan, Italy; School of Medicine, Università Vita-Salute San Raffaele, Milan, Italy. Electronic address:
HMGB1, a multitasking protein, is scrutinized here through the lens of the 'fuzzy interactions' driven by its intrinsically disordered regions (IDRs). Although the multiple intracellular and extracellular functions of this protein have been studied for decades, viewing HMGB1 as fuzzy and dynamic provides a novel perspective. Recent breakthroughs emphasize the crucial role of its IDRs, especially the acidic C-terminal tail, in mediating dynamic multivalent interactions.
View Article and Find Full Text PDFCureus
August 2025
Department of Neurosurgery, Toho University, Tokyo, JPN.
Herein, we report a case of immunoglobulin G4-related disease (IgG4-RD) that required differentiation from meningioma and dural metastasis based on neuroradiological imaging results, particularly focusing on magnetic resonance spectroscopy (MRS) and cerebral angiography findings. The patient was a 67-year-old woman who presented with left lower-limb weakness. She had been diagnosed with breast cancer 11 years earlier and was treated with surgical resection, followed by hormone therapy.
View Article and Find Full Text PDFNMR Biomed
October 2025
Department of Radiology, Tianjin First Central Hospital, Nankai University, Tianjin Institute of Imaging Medicine, Tianjin, China.
Objectives: Early diagnosis and timely treatment of renal fibrosis can improve the prognosis of patients with nephropathy. We aim to investigate the utility of multi-parametric MRI for evaluating early renal fibrosis and therapeutic efficacy in a rat model.
Methods: Eighty-four male SD rats receiving tail vein injection of adriamycin doxorubicin (ADR) to establish renal fibrosis models were utilized.