Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/gut.2009.191957 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impairment of Regenerative and Metabolic Pathways in Intestinal Organoids From Patients With MASLD-Cirrhosis.
Liver Int
October 2025
Division of Gastroenterology, Acireale Hospital, Azienda Sanitaria Provinciale di Catania, Catania, Italy.
Background And Aims: Gut-liver axis has been implicated in the pathophysiology of cirrhosis due to metabolic dysfunction-associated steatotic liver disease (MASLD), an in vitro model for studying epithelial gut dysfunction in MASLD is lacking. In this study, we aimed to characterise intestinal organoids derived from subjects with MASLD.
Materials And Methods: Intestinal organoids were obtained from duodenal samples of individuals with non-fibrotic MASLD and with MASLD-cirrhosis.
Single-cell atlas in the living fossil Yangtze sturgeon provides insight into the evolution of fish.
Genome Biol
September 2025
Fisheries Research Institute, Sichuan Academy of Agricultural Sciences, Chengdu, 611730, China.
Background: Fish are the largest group of vertebrates. Studying the characteristics, functions, and interactions of different fish cells is important for understanding their roles in disease and evolution. However, most single cell RNA-seq studies in fish are restricted to a few specific organs, leaving a comprehensive cell landscape that aims to characterize the heterogeneity and connections among body-wide organs largely unexplored.
View Article and Find Full Text PDFMouse intestine as a useful model for CFTR electrophysiology function analysis.
Methods Cell Biol
September 2025
Department of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, Italy; CEINGE-Biotecnologie Avanzate, Naples, Italy.
Cystic fibrosis (CF) is a genetic disorder primarily known for its severe impact on lung function, but it also significantly affects the digestive system, leading to complications such as intestinal blockages, malabsorption, inflammation, and microbial dysbiosis. The study of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) effects on intestinal physiology is critical for developing new effective treatments. This work highlights the use of the mouse intestine as a valuable model for analyzing cellular electrophysiology and CFTR function.
View Article and Find Full Text PDFCannulation of mesenteric lymphatic vessels in a murine model.
Methods Cell Biol
September 2025
Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, United States. Electronic address:
Mesentery is a crucial part of an animal's digestive system since it holds the intestine in place, while also contains the specialized lymph nodes and immune cells that help protect the intestines from infections and support the body's immune response in the abdominal cavity. Analyzing mesenteric lymph can help better understand the transport mechanisms and potential implications for various conditions, such as lymphatic disorders or underlying infections. The first step towards this is the precise collection of the mesenteric lymph.
View Article and Find Full Text PDFEllagic acid alleviates sepsis-induced intestinal injury by modulating gut microbiota and NF-κB-mediated MLCK/MLC signaling pathway.
Microb Pathog
September 2025
Department of Chinese Formulae, Heilongjiang University of Chinese Medicine, Harbin, China. Electronic address:
Sepsis is a systemic inflammatory response syndrome triggered by infection. Severe sepsis is associated with dysbiosis of the intestinal flora and impaired intestinal function. Ellagic acid (EA) is a natural compound known for its ability to inhibit bacteria and viruses, thereby preventing infections.
View Article and Find Full Text PDF