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DNA Parallel clamps with a polypurine strand linked to a polypyrimidine Hoogsteen strand containing locked nucleic acids bind their corresponding polypyrimidine targets with high affinity.
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http://dx.doi.org/10.1002/cbdv.200900230 | DOI Listing |
Adv Healthc Mater
September 2025
Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA.
Organ-on-chip (OOC) technologies, also called microphysiological systems (MPS), offer dynamic microenvironments that improve upon static culture systems, yet widespread adoption has been hindered by fabrication complexity, reliance on polydimethylsiloxane (PDMS), and limited modularity. Here, a modular MPS platform is presented, designed for ease of use, reproducibility, and broad applicability. The system comprises layered elastomeric inserts for dual monolayer cell culture, which is clamped within a reusable acrylic cassette for perfusion studies.
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September 2025
School of Electric and Electrical Engineering, Shanghai University of Engineering Science, Shanghai, China.
Wafer thickness is a critical parameter in semiconductor manufacturing, influencing production costs, and chip performance. Traditional measurement methods using clamping devices often introduce errors due to uneven positioning or unstable clamping. This study enhances the dual-probe chromatic confocal system by incorporating a diffractive optical element that splits white light into three beams, with spectrometer wave peak counts detecting wafer tilt.
View Article and Find Full Text PDFFront Vet Sci
August 2025
Department of Veterinary Surgery, College of Veterinary Medicine, Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea.
A 3-year-old Shiba Inu was presented to the hospital with a large skin defect (15 cm × 25 cm, oval shape) on the head and neck, involving the left auricle, caused by a traffic accident. Necrotic tissue caused by inflammation was observed in the area of the skin defect. To address this condition, a sugar dressing was applied for 17 days to promote granulation tissue formation before performing a superficial cervical axial pattern flap.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
July 2025
Department of Conservative and Endodontics, Farooqia Dental College, Mysuru, Karnataka, India.
Context: Accurate working length determination is essential for successful root canal therapy. This study compares the accuracy of two electronic apex locators-e-Magic Finder (EMF)-100 and WOODPEX I-with digital radiovisiography (RVG; Suni Ray) in determining root canal working length.
Aims: To evaluate and compare the accuracy of EMF-100 and WOODPEX I apex locators with RVG in determining the working length of root canals.
Phys Rev E
July 2025
Clark University, Department of Physics, Worcester, Massachusetts 01610, USA.
We investigate the formation of helical multifilament bundles and the torque required to achieve them as a function of applied twist. Hyperelastic filaments with circular cross sections are mounted parallel in a uniform circle onto end-clamps that can move along the twist axis depending on the applied axial load. With increasing twist, the filaments describe a hyperbolic hyperboloid surface before coming into contact in a circle and then packing in a tight helical bundle in the center with increasing twist.
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