Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Strategies effective for accelerating methotrexate removal in delayed methotrexate excretion have not been universally accepted. The authors report a case of a 12-year-old girl with osteosarcoma who developed acute renal failure immediately after the first administration of high-dose methotrexate. Plasma methotrexate was effectively removed with repeated charcoal hemoperfusion in addition to plasma exchange and leucovorin rescue. Charcoal hemoperfusion was most effective for reducing plasma methotrexate with approximately 50% of methotrexate being reduced during each of the procedures. No rebound increase in MTX levels was observed. The patient received further therapy with other cancer drugs and has been well for 3.5 years.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/08880010902976023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Functional Carbon-Based Materials for Blood Purification: Recent Advances Toward Improved Treatment of Renal Failure and Patient Quality of Life.
Bioengineering (Basel)
August 2025
Department of Chemistry, Pittsburg State University, 1701 South Broadway Street, Pittsburg, KS 66762, USA.
The accumulation of blood toxins, including urea, uric acid, creatinine, bilirubin, p-cresyl sulfate, and indoxyl sulfate, poses severe health risks for patients with renal failure. Effective removal strategies are essential to mitigate complications associated with chronic kidney disease (CKD) and improve patient outcomes. Functional carbon-based materials, such as activated carbon (activated charcoal) and graphene oxide, have emerged as promising adsorbents due to their large surface area, adjustable porosity, and biocompatibility.
View Article and Find Full Text PDFSurface Modification of Wood Activated Carbon by CVD of NH to Improve Its Micropore Volume and Adsorption to Carbamazepine.
Int J Nanomedicine
May 2025
School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, People's Republic of China.
Objective: This study enhanced wood-activated carbon using ammonia chemical vapor deposition (NH-CVD) to improve its adsorption properties for carbamazepine (CBZ).
Methods: Modification was done in a vacuum tube sintering furnace. We used X-ray photoelectron spectroscopy (XPS), Brunauer-Emmett-Teller (BET) method, and Fourier Transform Infrared Spectroscopy (FTIR) for characterization and analysis.
Successful Treatment of an Adolescent with Severe Amlodipine Poisoning with Charcoal Hemoperfusion.
Klin Padiatr
February 2025
Division of Pediatric Intensive Care, Ankara University School of Medicine, Ankara, Turkey.
Non-Cell-Based Extracorporeal Artificial Liver Systems: Historic Perspectives, Approaches and Mechanisms, Current Applications, and Challenges.
Artif Organs
June 2025
Department of Mechanical Engineering, University of Washington, Seattle, Washington, USA.
Background: Liver disease is a growing burden. Transplant organs are scarce. Extracorporeal liver support systems (ELSS) are a bridge to transplantation for eligible patients.
View Article and Find Full Text PDF