Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Extravascular lung water includes all of the fluid within the lung but outside of the vasculature. Lung water increases as a result of increased hydrostatic vascular pressure or from an increase in lung endothelial and epithelial permeability or both. Experimentally, extravascular lung water has been measured gravimetrically. Clinically, the chest radiograph is used to determine whether extravascular lung water is present but is an insensitive instrument for determining the quantity of lung water. Bedside measurement of extravascular lung water in patients is now possible using a single indicator thermodilution method. This review critically evaluates the experimental and clinical evidence supporting the potential value of measuring extravascular lung water in patients using the single indicator method.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770794 | PMC |
| http://dx.doi.org/10.1152/ajplung.00127.2009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Unveiling Condensed Aromatic Amines as Noteworthy Genotoxic Components in PM Dissolved Organic Matter.
Environ Sci Technol
September 2025
State Key Laboratory of Advanced Environmental Technology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
The potential of PM to cause lung cancer has been well established; however, evidence regarding which specific components are responsible remains limited. We investigated dissolved organic matter (DOM) in PM using high-resolution mass spectrometry (HRMS) and cellular DNA damage assays to elucidate molecular composition and sources of carcinogenic components. Our analysis revealed hundreds of genotoxic compounds, with condensed aromatic amines predominating in number, abundance, and contribution to overall genotoxicity.
View Article and Find Full Text PDFContamination profile and potential human health risks of radon in groundwater of southwest region of Punjab, India.
Environ Geochem Health
September 2025
Environmental Hydrology Division, National Institute of Hydrology, Roorkee, 247667, India.
Radon (Rn) is a naturally occurring radioactive gas produced by the decay of uranium-bearing minerals in rocks and soils. Long-term exposure to elevated radon levels in drinking water is associated with an increased risk of stomach and lung cancers. This study aims to assess the concentration of radon in groundwater and evaluate its potential health risks in six cancer-affected districts, i.
View Article and Find Full Text PDFEvaluation of lung oxidative stress and inflammatory state using exhaled breath condensate analysis in early-life arsenic exposure.
J Breath Res
September 2025
Department of Anatomy, Physiology, and Cell Biology, , University of California Davis, School of Veterinary Medicine, Davis, California, 95616-5270, UNITED STATES.
Millions of people worldwide are exposed to environmental arsenic in drinking water, resulting in both malignant and nonmalignant diseases. Interestingly, early life exposure by itself is sufficient to produce higher incidences of these diseases later in life. Based on the delayed onset of disease, we hypothesized that early life arsenic exposure would also induce long-term alterations in the metabolic profile.
View Article and Find Full Text PDFInhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
ACS Nano
September 2025
Department of Emergency and Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou 215124, China.
Acute lung injury (ALI) is characterized by the excessive accumulation of reactive oxygen species (ROS), which triggers a severe inflammatory cascade and the destruction of the alveolar-capillary barrier, leading to respiratory failure and life-threatening outcomes. Considering the limitations and adverse effects associated with current therapeutic interventions, developing effective and safe strategies that target the complex pathophysiological mechanisms of ALI is crucial for improving patient outcomes. Herein, we developed an inhalable, multifunctional nanotherapeutic (MSCNVs@CAT) by encapsulating catalase (CAT) in mesenchymal-stem-cell-derived nanovesicles (MSCNVs).
View Article and Find Full Text PDFSaturation of respiratory strain during robotic hysterectomy in obese women with endometrial cancer.
J Robot Surg
September 2025
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, UT Health San Antonio, 7703 Floyd Curl Drive, 7836, San Antonio, TX, 78229-3900, USA.
To evaluate intraoperative ventilatory mechanics during robotic-assisted hysterectomy in obese women with endometrial cancer and introduce the concept of a physiologic "ceiling effect" in respiratory strain. We conducted a retrospective cohort study of 89 women with biopsy-confirmed endometrial cancer who underwent robotic-assisted total hysterectomy between 2011 and 2015. Intraoperative ventilatory parameters, including plateau airway pressure and static lung compliance, were recorded at five-minute intervals.
View Article and Find Full Text PDF