98%
921
2 minutes
20
Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) levels in a total of 25 food items in Taiwan were surveyed. It was observed that shellfish and saltwater fish possessed the highest PCDD/Fs levels, 9.82 and 3.60 pg WHO-TEQ/g, respectively, on the lipid basis. The dietary intakes of humans at the ages of 12-18, 19-64, and over 65 were determined. The estimated intake were between 21.8 pg (female teenagers) and 37.6 pg (male seniors) WHO-TEQ/day; the levels varied with the dietary habits. The PCDD/F intakes for all human groups are far below the tolerable limit of 70 pg WHO-TEQ/kg b.w./month. In addition, the daily PCDD/F intake levels for duck-farmers consuming average and large amounts of PCDD/F contaminated duck eggs were examined. The result shows that consuming more than one duck egg with level higher than 10 pg WHO-TEQ/g lipid of PCDD/Fs per day could lead to a PCDD/F intake level higher than the tolerable limit. However, for normal population, there is a little risk to ingest intolerable amount of PCDD/Fs because of consuming contaminated duck eggs.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jhazmat.2008.08.040 | DOI Listing |
Ecotoxicol Environ Saf
September 2025
Department of Urology, Urology Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China; Department of Urology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China; Fujian Key Labo
Objective: Polychlorinated dibenzo-p-dioxins (PCDDs) present a significant long-term threat to human health attributable to their toxicological properties, chemical stability and propensity for bioaccumulation. This study seeks to explore the correlation between PCDDs exposure and prostate cancer (PCa) through comprehensive analysis.
Methods: The multi-dimensional analysis was conducted based on various online databases.
Environ Sci Technol
August 2025
CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China.
The catalytic mechanisms underlying the formation of polybrominated dibenzo--dioxins and dibenzofurans (PBDD/Fs) have emerged as a critical environmental concern, particularly regarding the roles of metal- and metalloid-based catalysts. Although these catalysts are recognized as crucial agents for the formation of PBDD/Fs, there is still significant knowledge gaps in identifying the active species and quantifying their catalytic activities. This study systematically investigates four key reaction pathways governing PBDD/Fs formation: aromatic bromination, the Deacon reaction, the precursor, and the de novo synthesis process.
View Article and Find Full Text PDFFood Chem Toxicol
August 2025
Mass Spectrometry and Dioxin Analysis Laboratory, INRASTES, NCSR "Demokritos", Neapoleos 27, 15310, Athens, Greece. Electronic address:
Human dietary exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), dioxin-like polychlorinated biphenyls (DL-PCBs) and non dioxin-like polychlorinated biphenyls (NDL-PCBs) is of worldwide scientific concern due to the health hazards associated with these compounds. In this study an estimation of the dietary intake of adolescents and adults in Greece was attempted for the first time. Representative samples from food categories widely consumed in Greece were collected and analyzed during a period of 21 years (2002-2022).
View Article and Find Full Text PDFChemosphere
September 2025
Mass Spectrometry Laboratory, University of Liège, 4000, Liège, Belgium. Electronic address:
In this study, we evaluated the quantitative capabilities of a GC-APCI trapped ion mobility (TIMS) TOF platform for the determination of ultra-trace levels of polychlorinated dibenzo-p-dioxins (PCDD/Fs) and polychlorinated biphenyls (PCBs) in complex food matrices. Using a Bruker timsTOF Pro 2 instrument, three fat-based proficiency test samples - fish oil, palm oil, and milk fat - were analyzed and compared to a validated GC-sectorHRMS method, in accordance with the criteria set by Commission Regulation (EU) 2017/644. Linearity was confirmed across broad dynamic ranges, with relative response factor (RRF) precision consistently below 20 %.
View Article and Find Full Text PDFJAMA Netw Open
August 2025
Tibor Rubin Veterans Affairs Medical Center, Long Beach, California.
Importance: Agent Orange (AO), a toxic herbicide mixture contaminated with carcinogenic dioxin, was widely used during the Vietnam War. Although epidemiologic evidence suggests AO exposure is associated with increased lymphoid malignant neoplasm risk, the details of this association and its potential interaction with genetic factors remain unclear.
Objective: To evaluate (1) whether AO exposure was associated with increased risk of lymphoid malignant neoplasms, (2) associations of polygenic risk scores (PRSs) in specific lymphoid malignant neoplasms, and (3) whether there was a genetic component × exposure interaction associated with increased risk of developing lymphoid malignant neoplasms.