Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The impact of isolated diastolic dysfunction (IDD) and systolic dysfunction (SD) on health-related quality of life (HRQOL) is unknown.
Methods And Results: To evaluate HRQOL in patients with IDD and SD under treatment, information on outpatients aged 60-84 years was extracted from the records of 4,500 consecutive individuals who underwent echocardiographic examination at Sado General Hospital. The medical records of these patients were reviewed and a questionnaire, including the Medical Outcome Study Short Form 36, was mailed to 71 IDD and 99 SD patients; answers were obtained from 66 and 91 patients, respectively. The HRQOL of patients with cardiac dysfunction was impaired even when echocardiographic parameters improved with treatment. Patients with IDD showed an impairment of HRQOL similar to those with SD. Compared with males, female patients had a larger and more significant reduction in the physical and mental components of the HRQOL score. These scores correlated positively with exercise capacity in patients with IDD or SD.
Conclusions: Impaired HRQOL, in both its mental and physical components, is a serious problem for IDD and SD patients under treatment. Because exercise intolerance may underlie the reduced HRQOL, improving exercise capacity could be an important target for managing outpatients with heart failure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1253/circj.cj-07-0842 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
BackgroundIndividuals with intellectual and developmental disabilities (IDD) face significant health disparities, often exacerbated by ethical and legal complexities in nursing care. Nurses are frequently challenged to balance autonomy, informed consent, patient safety, and human rights, especially in settings with unclear guidelines or insufficient training. This narrative review explores the ethical and legal considerations in nursing care for individuals with IDD, aiming to highlight challenges and propose best practices.
View Article and Find Full Text PDFSagittal-oriented articular processes and intervertebral disc degeneration phenotypes can concurrently lead to an increased presence of annulus tears in the cranial adjacent motion segment : a clinical review and biomechanical simulation.
Bone Joint Res
September 2025
Department of Orthopedics, Luzhou Key Laboratory of Orthopedic Disorders, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Aims: Intervertebral disc degeneration (IDD) and sagittal-oriented articular processes can restrict motility and increase stiffness of the motion segment, potentially causing compensatory stress and higher motility in adjacent segments. It is unclear if these factors trigger IDD progression in adjacent segments. This study aimed to elucidate this using functional MRI, and identify biomechanical mechanisms with a validated numerical model.
View Article and Find Full Text PDFPediatric Imminent Death Donation: Is It Ethical?
J Pain Symptom Manage
August 2025
Division of Palliative Medicine, Nemours Children's Health, Wilmington, Delaware; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA. Electronic address:
Imminent death donation (IDD) is a form of organ donation that would occur just prior to the withdrawal of life-sustaining technology (WOLST). While IDD may offer a valuable opportunity for organ donation, for example when donation after circulatory death (DCD) is not feasible, it raises significant ethical concerns, particularly in pediatric cases. Living organ donation from minors is performed only under exceptional circumstances, and with specific criteria including age-appropriate assent and a clear benefit to both donor and recipient.
View Article and Find Full Text PDFDirect support professional perspectives on the value of virtual healthcare for adults with intellectual and developmental disabilities: Trends over four years.
Disabil Health J
August 2025
Azrieli Adult Neurodevelopmental Centre, Centre for Addiction and Mental Health, 1025 Queen St. W, Toronto, Ontario, M6J 1H1, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.
Background: Direct support professionals (DSPs) often play a critical role in supporting healthcare interactions for people with intellectual and developmental disabilities (IDD) but little is known about their experience supporting virtual healthcare.
Objective: This study explored utilization of virtual care and DSP experiences of supporting virtual care at four time points in Ontario, Canada.
Methods: DSPs in Ontario were invited to participate in an online survey in 2020 (n = 867), 2021 (n = 428), 2022 (n = 698) and 2023 (n = 603).
Muscone suppresses inflammation and senescence of nucleus pulposus via p53 signalling during intervertebral disc degeneration.
Sci Rep
August 2025
Spine Center, Department of Orthopedics, Shanghai Changzheng Hospital Affiliated to Naval Medical University, 415th Fengyang Road, Huangpu District, Shanghai, 200003, China.
Intervertebral disc degeneration (IDD) is a major cause of chronic low back pain, the mechanism of which is still unclear. Inflammation-induced extracellular matrix metabolism (ECM) dysregulation in the nucleus pulposus (NP) and NP cell senescence are known to be the key causes of IDD. However, few drugs can reliably alleviate ECM dysregulation and NP cell senescence.
View Article and Find Full Text PDF