RadC, a misleading name?

J Bacteriol

Laboratoire de Microbiologie et Génétique Moléculaires, UMR 5100, CNRS, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 09, France.

Published: August 2008


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Article Abstract

The pfam04002 annotation describes RadC as a bacterial DNA repair protein. Although the radC gene is expressed specifically during competence for genetic transformation in Streptococcus pneumoniae, we report that radC mutants exhibit normal uptake and processing of transforming DNA. They also display normal sensitivity to DNA-damaging agents, providing no support for the rad epithet.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519389PMC
http://dx.doi.org/10.1128/JB.00425-08DOI Listing

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