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Article Abstract

Using a large consortium of undergraduate students in an organized program at the University of California, Los Angeles (UCLA), we have undertaken a functional genomic screen in the Drosophila eye. In addition to the educational value of discovery-based learning, this article presents the first comprehensive genomewide analysis of essential genes involved in eye development. The data reveal the surprising result that the X chromosome has almost twice the frequency of essential genes involved in eye development as that found on the autosomes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034635PMC
http://dx.doi.org/10.1534/genetics.107.077735DOI Listing

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