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Medicine (Baltimore)
September 2025
Department of Oncology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China.
Numerous observational studies have suggested links between sex hormones and various autoimmune diseases (ADs). However, the causality of these associations remains uncertain. This study employs Mendelian randomization (MR) analysis to investigate the causal relationship between sex hormones and ADs risk.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
September 2025
Department of Endocrinology and Metabolic Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.
To investigate the changes in and correlations between melanin-concentrating hormone (MCH) and androgen levels in the serum of patients with polycystic ovary syndrome (PCOS), aiming to provide a novel research perspective for its diagnosis. A cross-sectional study. A total of 307 subjects were enrolled from the physical examination center and endocrinology clinic of the Affiliated Hospital of Zunyi Medical University from June 2023 to June 2024.
View Article and Find Full Text PDFAm J Mens Health
August 2025
Faculty of Medical Sciences, Goce Delcev University, Stip, North Macedonia.
Age-related decline in dehydroepiandrosterone (DHEA) and its sulfate metabolite, dehydroepiandrosterone-sulfate (DHEAS), affects steroid synthesis in men. DHEA(S) acts as a direct neurosteroid and weak androgen and is the unique steroid unaffected by dutasteride's inhibitory effect on 5α reductases. This study examined the relationship between dutasteride's side effects, specifically erectile dysfunction (ED) and mood disorders, and the age-related decline in DHEAS.
View Article and Find Full Text PDFPsychoneuroendocrinology
October 2025
Center on Sex⁎Gender, Allostasis, and Resilience, Research Center of the Montreal Mental Health University Institute, 7331, Rue Hochelaga, Montreal, QC H1N 3V2, Canada; Department of Psychiatry and Addiction, University of Montreal, Montreal, QC, Canada. Electronic address: robert-paul.juster@umon
Sexual orientation is sometimes correlated to sexually polymorphic cognitive performance. Furthermore, hormones also modulate cognitive performance that may differ according to sexual orientation. Our study explores potential differences in cognitive performance and hormone levels across a diversity of sexual orientations that include sexually diverse (SD) people and those who identify as heterosexual.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
August 2025
Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University, Szczecin, Poland.
Background: This cross-sectional study aimed to examine the relationship between total testosterone (TT) levels, the diagnosis of testosterone deficiency syndrome (TDS), and high-sensitivity C-reactive protein (hsCRP) concentrations in aging men. The analysis also included selected hormonal and anthropometric parameters.
Methods: Serum hsCRP levels were measured.