Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
In recent times, airborne microorganisms and their constituents have become prominent safety and health concern. Ongoing climatic changes coupled with unwarranted human activities have significantly deteriorated the ambient air quality. In certain environments, airborne algae contribute significantly to the total biological load of the atmosphere, hitherto dominated by bacteria and fungi. Present study was aimed to investigate the allergenic potency of two frequent viable algal forms i.e., Phormidium fragile and Nostoc muscorum found in the atmosphere of Varanasi City, India. To test the allergenic potency, crude extracts of these strains were subjected to intra-dermal allergy test and subsequent leukocyte counts, which revealed their allergenic nature. Both the species varied in their allergenic potency. N. muscorum appeared to be more allergenic than P. fragile. However, when the allergens were mixed in equal amounts, the severity of allergenicity increased significantly. A limited pattern of cross-reactivity between the species was also evident.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ecoenv.2006.08.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Designing a multi-epitope vaccine against the midgut-specific fibrinogen-related protein 1(FREP1) of Anopheles stephensi to enhance protection against the malaria parasite: a step beyond traditional vaccine development approaches.
Biotechnol Lett
September 2025
Department of Genetics, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Malaria has been a prominent health burden for decades globally. The complex life cycle of Plasmodium made numerous challenges in finding an effective candidate for developing a potent transmission-blocking vaccine (TBV) against malaria. A wide variety of genes of Anopheles mosquitoes' midgut and salivary gland play a pivotal role in the Plasmodium invasion and transmission inside the mosquito body.
View Article and Find Full Text PDFIdentification of IgE Epitopes and Analysis of Critical Amino Acid Residues in Fish Parvalbumin.
J Agric Food Chem
August 2025
Department of Nutrition and Food Hygiene, School of Public Health, Qingdao University, Qingdao 266071, China.
The increasing incidence of fish allergy, primarily triggered by parvalbumin (PV), has become a significant public health issue. Although novel PVs are increasingly being characterized, the allergenic epitopes have not been comprehensively identified. This study aimed to explore the IgE epitopes of PV and identify critical amino acid residues, while systematically assessing their connection to the IgE-binding capacity.
View Article and Find Full Text PDFStructure-based design of a multi-epitope vaccine candidate against marburg virus using immunoinformatics and dynamics simulations.
J Mol Graph Model
December 2025
Gilgamesh Ahliya University, Baghdad, Iraq. Electronic address:
The Marburg virus, a close relative of the Ebola virus, is a menacing Filovirus known for its devastating outbreaks in Germany and recent outbreaks in Guinea and Tanzania. This deadly pathogen triggers severe hemorrhagic fever, posing a grave threat to public health and demanding urgent attention from the global medical community. The amino acid sequence and PDB of the Envelope glycoprotein (GP) were extracted from RCSB for use in predicting epitopes (IEDB server).
View Article and Find Full Text PDFAirborne exposure-induced occupational type I allergy to Tenebrio molitor: Case report and studies on immunological reactivity.
Allergol Select
July 2025
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, and.
This occupational case report describes a 28-year-old woman, employed since November 2020 as a research assistant working with mealworms (), who developed symptoms of mild shortness of breath and severe redness and swelling of the eyes in early 2022, leading to the diagnosis of occupational allergic asthma due to respiratory sensitization to mealworm. Subsequent tests confirmed mono-sensitization to and additional cross-sensitization to flour beetle (). Further studies aimed to determine the antigenic and allergenic potency of different protein fractions and rearing material isolated from regarding protein pattern and immunological activity by -specific polyclonal rabbit IgG and human IgE.
View Article and Find Full Text PDFTRIM33 prevents the exacerbation of allergic asthma by restricting the overactivation of alveolar macrophages.
Mucosal Immunol
July 2025
Institute for Immunology, School of Basic Medical Sciences, Tsinghua University, Beijing 10084, China; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 10084, China; Beijing Key Laboratory of Immunological Research of Allergy (LIRA), Tsinghua University, Beijing 100084, China.
Alveolar macrophages (AMs) and dendritic cells (DCs) are the two major types of primary innate immune cells in allergic asthma and their functions were elaborately regulated during the progression of asthma. Tripartite motif-containing protein 33 (TRIM33) is a multifunctional protein that regulates differentiation and function of immune cells. However, its role in AMs and DCs in the context of allergic asthma remained unclear.
View Article and Find Full Text PDF