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A method for calculating the pressure tensor in constant-volume Monte Carlo simulations of convex bodies is presented. In contrast to other approaches, the method requires only an isotropic scaling of the simulation box and the counting of simple geometric quantities characterizing overlapping pairs. Nonsphericity presents no special difficulties. The result is expressed as a sum of pairwise contributions and can therefore be used to compute pressure tensor profiles in a conventional way.
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http://dx.doi.org/10.1063/1.2202352 | DOI Listing |
J Phys Chem Lett
September 2025
Department of Earth System Sciences, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
We present a systematic high-pressure investigation of the chlorine-functionalized two-dimensional hybrid perovskite (ClPMA)PbI, integrating high-pressure synchrotron powder X-ray diffraction (HP-PXRD), photoluminescence spectroscopy (HP-PL), and first-principles density functional theory (DFT) calculations. Under hydrostatic compression up to 6.18 (±0.
View Article and Find Full Text PDFNMR Biomed
October 2025
High-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
The human kidneys play a pivotal role in regulating blood pressure, water, and salt homeostasis, but assessment of renal function typically requires invasive methods. Deuterium metabolic imaging (DMI) is a novel, noninvasive technique for mapping tissue-specific uptake and metabolism of deuterium-labeled tracers. This study evaluates the feasibility of renal DMI at 7-Tesla (7T) to track deuterium-labeled tracers with high spatial and temporal resolution, aiming to establish a foundation for potential clinical applications in the noninvasive investigation of renal physiology and pathophysiology.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurology, Tiantai People's Hospital of Zhejiang Province (Tiantai Branch of Zhejiang Provincial People's Hospital), Hangzhou Medical College, Taizhou, China.
Cerebral small vessel disease (CSVD) has recently garnered extensive attention owing to its significant disease burden, insidious onset, and the absence of effective specific treatments. Poor lifestyle habits and chronic diseases are closely linked to its occurrence and development, eventually resulting in cognitive dysfunction. Therefore, improvement of lifestyle, stable blood pressure, effective glucose lowering, low-salt and low-fat diet, smoking cessation, moderate exercise and adequate sleep are the keys to preventing cognitive dysfunction in cerebral small-vessel disease.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Objective: The aims of the study were to investigate differences in cortical mean diffusivity (MD) among idiopathic normal-pressure hydrocephalus (INPH) patients, Alzheimer's disease (AD) patients, and healthy controls, and to analyze mean MD among INPH and AD groups in INPH-specific areas showing distinctive cortical MD changes for distinguishing INPH from AD.
Methods: Forty-two INPH patients, 51 AD patients, and 23 healthy controls were imaged with MRI, including diffusion tensor imaging MR images, for surface-based analysis across the entire brain.
Results: Compared with healthy controls, INPH patients showed a statistically significant reduction in MD in the high convexity of the frontal, parietal, and occipital cortical regions.
Diabetes Care
August 2025
Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Objective: Type 2 diabetes (T2D) and its associated complications develop heterogeneously over decades, but few studies span the progression from prediabetes to clinical events. We investigated whether long-term metabolic trajectories beginning in prediabetes delineate subgroups with differential complication risk.
Research Design And Methods: Clinical data from 1,732 Diabetes Prevention Program/Outcomes Study participants (follow-up 19 years) were analyzed across 12 phenotypes.