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Fourteen mineral and trace elements (Al, Ba, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Ni, Pb, Sr and Zn) were determined in the herbs and their infusions consumed for medical purposes in Turkey such as chamomile (Matricaria chammomile L.), fennel (Foeniculum vulgare), linden (Tilia vulgaris), nettle (Urtica dioical), rosehip (Fr.Rosa caninae), sage (Salvia officinalis) and senna tea (Cassia anqustifolia). Microwave digestion procedure was applied under optimized conditions for dissolution of medicinal herbs. Element concentrations in the medicinal herbs and their infusions were determined by FAAS and ICP-AES. The accuracy and precision were verified against a GBW 07605 Poplar leaves and Tea certified reference material. The mineral and trace element content of medicinal herbs and their infusions showed a wide variability. However, distribution of the elements in the infusions is not high and it is nil especially for Cd, Co, Cr and Pb.
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http://dx.doi.org/10.1016/j.scitotenv.2005.04.016 | DOI Listing |
Appl Biochem Biotechnol
September 2025
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, 51452, Qassim, Saudi Arabia.
Viruses are minuscule entities that cannot survive independently without a Living host. Pathogenic viruses pose a significant threat to global health, resulting annually in the deaths of thousands of people. Recent studies indicate that medicinal plants may serve as an effective source of sustainable natural antiviral agents.
View Article and Find Full Text PDFMol Divers
September 2025
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, Xinjiang, China.
Aurora kinases are a group of serine/threonine kinases essential for cell mitosis, comprising Aurora A, B, and C. However, the Aurora B is overexpressed in multiple tumors and the aurone has been proved to exhibit potent inhibitory activity against Aurora B kinase by our group. The indolinone was considered as an aurone scaffold hopping analog, and the indolinone-based Aurora B inhibitor library (3577 molecules) was constructed by FBDD strategy.
View Article and Find Full Text PDFNat Prod Rep
September 2025
State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Covering: up to April 2025Bacterial aromatic polyketides represent a notable class of natural products that have found extensive applications in clinical treatments. In their biosynthesis, oxidative rearrangements represent critical transformations that typically afford diverse scaffolds, structural rigidity, and biological activities. In this context, it is evident that redox enzymes are frequently implicated in various rearrangement processes, whereby they facilitate the transformation of pathway precursors into mature natural products.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Pharmacy, Jiblah University for Medical and Health Science, Ibb, Yemen.
Background: () Resin has been used in traditional medicine for millennia because of its anti-inflammatory, antibacterial, and wound-healing characteristics. Recent research has proved its medicinal promise, particularly against resistant bacterial strains and oxidative stress.
Objective: This study seeks to assess the antimicrobial and antioxidant properties of resin, extracted with ethanol, and to formulate a topical cream for dermatological use, specifically targeting skin infections and inflammatory conditions such as acne.
JTO Clin Res Rep
October 2025
Clinical Research Center (CRC), Medical Pathology Center (MPC), Cancer Early Detection and Treatment Center (CEDTC), and Translational Medicine Research Center (TMRC), Chongqing University Three Gorges Hospital, Wanzhou District, Chongqing, People's Republic of China.
NUT carcinoma is a rare and highly aggressive malignancy characterized by rapid progression, resistance to conventional therapies, and an extremely poor prognosis. This report presents a 36-year-old patient with stage IIIB primary pulmonary NUT carcinoma who achieved remarkable clinical outcomes with NHWD-870 monotherapy, a novel BET inhibitor. After just 1 month of treatment, imaging revealed a partial response, and a complete response was achieved within 5 months.
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