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Objective: To investigate the cause of unilateral vocal cord paralysis in aged.
Method: Fifty-one patients with unilateral vocal cord paralysis in aged were retrospectively analyzed.
Result: The main cause of unilateral vocal cord paralysis in aged was malignant tumor.
Conclusion: Extralaryngeal malignant tumor should be greatly suspected in aged with unilateral vocal cord paralysis. When the cause could not be identified through systematic examination, the patient should be followed up regularly.
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PLoS One
September 2025
Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan.
Glottic insufficiency results from impaired vocal fold contact, leading to a gap between the folds and manifesting as hoarseness and respiratory difficulties. Vocal folds injection is a commonly utilized therapeutic approach to rectify this gap by augmenting vocal folds volume; however, the optimal injectable material remains undetermined. Dedifferentiated fat cells (DFATs), derived from mature adipocytes, exhibit robust proliferative capacity and multipotency, establishing them as potential candidates for treating glottic insufficiency.
View Article and Find Full Text PDFJ Voice
August 2025
Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Medicine and Surgery, University of Enna "Kore", Enna, Italy. Electronic address:
Background: Laryngeal reinnervation is a promising therapeutic option for unilateral vocal fold paralysis (UVFP). However, the efficacy of the different techniques remains controversial.
Objectives: To systematically evaluate clinical outcomes and surgical approaches employed for laryngeal reinnervation in UVFP, using both objective and subjective parameters.
Sci Rep
August 2025
Department of Information Engineering, Università degli Studi di Firenze, Florence, Italy.
Voice disorders represent a common medical condition affecting up to 16.9% of the general population, with unilateral vocal fold paralysis (UVFP) being particularly severe. This condition causes breathy dysphonia, maladaptive articulatory behaviours, and cortical alterations in sensory processing.
View Article and Find Full Text PDFFolia Phoniatr Logop
August 2025
Objectives: Type I medialization thyroplasty (MT) is one of the standard procedures in patients having permanent unilateral vocal fold paralysis (UVFP) with insufficient glottal closure. The objective of this study was to evaluate the clinical outcome in patients with UVFP 7 weeks post implantation using the novel APrevent® VOIS (VOIS) implant with its adjustable balloon.
Methods: The VOIS implant was applied in 32 Patients with UVFP during MT.
Cureus
July 2025
Anesthesiology and Perioperative Medicine, OhioHealth Doctors Hospital, Columbus, USA.
This case report describes the airway course of a 52-year-old male who required emergent exploratory laparotomy for suspected gastrointestinal perforation. The patient had underlying subglottic stenosis and unilateral vocal cord paralysis, as well as a history of significant cardiopulmonary disease. Attempts at intubation using standard tube sizes were unsuccessful.
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