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Background: Fat is theoretically the ideal implant for vocal fold augmentation because it is soft, easily available and biocompatible. However, reabsorption is a frequent cause of long-term failure.
Objective: We prospectively tested Coleman's "lipostructure" technique used for facial recontouring in the treatment of glottic incompetence.
Study Design And Setting: Fourteen patients (aged 18-74 years, mean 48) with breathy dysphonia secondary to laryngeal hemiplegia (7) or anatomical defects (7) underwent vocal fold lipoinjection. Fat harvested by liposuction was centrifuged, and the fat cell layer injected into the vocalis muscle. The patients underwent pre- and postoperative videolaryngostroboscopy, maximum phonation time (MPT) measurements, GRBAS perceptual evaluations, and Voice Handicap Index (VHI) self-assessments.
Results: Voice quality improved soon after surgery and remained stable over 3-26 months (mean 10.6), being confirmed by the GRBAS, MPT and VHI evaluations ( P < 0.005). The results were best in the seven patients with paralytic dysphonia.
Conclusion: Lipostructure is a valuable technique for voice rehabilitation in glottic incompetence.
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http://dx.doi.org/10.1016/j.otohns.2004.09.022 | DOI Listing |
J Acoust Soc Am
September 2025
Department of Head and Neck Surgery, University of California, Los Angeles, 31-24 Rehab Center, 1000 Veteran Avenue, Los Angeles, California 90095-1794, USA.
The goal of this study was to understand the interaction between the voice source spectral shape, formant tuning, and fundamental frequency in determining the vocal tract contribution to vocal intensity. Computational voice simulations were performed with parametric variations in both vocal fold and vocal tract configurations. The vocal tract contribution to vocal intensity was quantified as the difference in the A-weighted sound pressure level between the radiated sound pressure and the sound pressure at the glottis.
View Article and Find Full Text PDFJ Voice
September 2025
Department of Speech and Language Therapy, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey. Electronic address:
Objectives: In individuals over 65, age is an essential factor in voice changes. Acoustic and aerodynamic norms guide clinicians in interpreting clinical voice assessment results. This study aimed to present aerodynamic-acoustic voice measurements in older individuals with no voice complaints.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan.
Glottic insufficiency results from impaired vocal fold contact, leading to a gap between the folds and manifesting as hoarseness and respiratory difficulties. Vocal folds injection is a commonly utilized therapeutic approach to rectify this gap by augmenting vocal folds volume; however, the optimal injectable material remains undetermined. Dedifferentiated fat cells (DFATs), derived from mature adipocytes, exhibit robust proliferative capacity and multipotency, establishing them as potential candidates for treating glottic insufficiency.
View Article and Find Full Text PDFLaryngoscope
September 2025
UAB Voice Center, Department of Otolaryngology-Head and Neck Surgery, Heersink School of Medicine, Birmingham, Alabama, USA.
Objectives: To examine factors that direct decisions in the treatment of glottic insufficiency and propose a paradigm that may assist in treatment decision-making in glottic insufficiency.
Methods: A retrospective chart review was completed of 73 patients with vocal fold atrophy, presbyphonia, or vocal fold motion impairment, including diagnosis, Voice Handicap Index-10 (VHI-10), Voice Problem Impact Scales (VPIS), Glottal Function Index (GFI), Eating Assessment Tool-10 (EAT-10), Consensus Auditory Perceptual Analysis of Voice (CAPE-V), glottal gap size, stimulability, treatment decisions, and outcomes. Univariate and multivariate logistic regression analyses were performed to identify which variables predicted initial treatment recommendation.
Trop Doct
September 2025
Professor and Head, Department of Dermatology, Venereology and Leprosy, King George's Medical University, Lucknow, Uttar Pradesh, India.
A 56-year old immuno-competent male from a non-endemic region in India presented with progressive weight loss, hoarseness of voice and widespread cutaneous lesions, including leonine facies, genital nodules and diffuse scaling. Magnetic resonance imaging of the neck revealed oedematous thickening of the false vocal cords, epiglottis and aryepiglottic folds, suggesting laryngeal involvement. All routine investigations were normal.
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