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Many factors must be considered in planning and implementing research. Scientific reasons for decisions are important, but so are practical considerations. The suggestions made throughout this column are based on experience and may seem to some to be simply "common sense." However, the importance of these practical, common sense considerations cannot be minimized. These practical suggestions are intended to bring into focus the fact that the research process is not that different from other decision-making processes: In research as in life, there are multiple ways to get from point A to point B, and none of them is inherently right or wrong. The choices the researcher makes in designing and implementing a study must be clearly described and must be based on the research goals, the theoretical framework used, and the resources available. Potential nurse researchers should not be intimidated by the task at hand. Rather, they should be comforted by the fact that the same processes they use in making decisions about clinical practice can be employed in designing and implementing research studies.
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http://dx.doi.org/10.1891/0730-0832.23.5.71 | DOI Listing |
J Phys Chem Lett
September 2025
Department of Chemistry, Oregon State University, 153 Gilbert Hall, Corvallis, Oregon 97331, United States.
Carbon dots (CDs) represent a new class of nontoxic and sustainable nanomaterials with increasing applications. Among them, bright and large Stokes-shift CDs are highly desirable for display and imaging, yet the emission mechanisms remain unclear. We obtained structural signatures for the recently engineered green and red CDs by ground-state femtosecond stimulated Raman spectroscopy (FSRS), then synthesized orange CDs with similar size but much higher nitrogen dopants than red CDs.
View Article and Find Full Text PDFSports Med Open
September 2025
Division of Physiological Sciences, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Newlands, Cape Town, 7725, South Africa.
Background: In tackle-collision sports, the tackle has the highest incidence, severity, and burden of injury. Head injuries and concussions during the tackle are a major concern within tackle-collision sports. To reduce concussion and head impact risk, evaluating optimal tackle techniques to inform tackle-related prevention strategies has been recommended.
View Article and Find Full Text PDFArch Orthop Trauma Surg
September 2025
Medical Faculty, University of Zurich (UZH), Zurich, Switzerland.
Background: Distal triceps tendon rupture is related to high complication rates with up to 25% failures. Elbow stiffness is another severe complication, as the traditional approach considers prolonged immobilization to ensure tendon healing. Recently, a dynamic tape was designed, implementing a silicone-infused core for braid shortening and preventing repair elongation during mobilization, thus maintaining constant tissue approximation.
View Article and Find Full Text PDFACS Synth Biol
September 2025
School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona 85281, United States.
Cellular resource limitations create unintended interactions among synthetic gene circuit modules, compromising circuit modularity. This challenge is particularly pronounced in circuits with positive feedback, where uneven resource allocation can lead to Winner-Takes-All (WTA) behavior, favoring one module at the expense of others. In this study, we experimentally implemented a Negatively Competitive Regulatory (NCR) controller using CRISPR interference (CRISPRi) and evaluated its effectiveness in mitigating WTA behavior in two gene circuits: dual self-activation and cascading bistable switch.
View Article and Find Full Text PDFA compact low-level RF (LLRF) control system based on RF system-on-chip (RFSoC) technology has been designed for the Advanced Concept Compact Electron Linear-accelerator (ACCEL) program, which has challenging requirements in both RF performance and size, weight, and power consumption (SWaP). The compact LLRF solution employs the direct RF sampling technique of RFSoC, which samples the RF signals directly without any analog upconversion and downconversion. Compared with the conventional heterodyne based architecture used for the LLRF system of a linear accelerator (LINAC), the elimination of analog mixers can significantly reduce the size and weight of the system, especially with LINAC requiring a larger number of RF channels.
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