Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Although gabapentin was originally developed for treating partial seizures, it has been used mainly to treat various peripheral neuropathic pain conditions; however, there is very limited experience with gabapentin for the treatment of pain conditions of the central nervous system like central post-stroke pain syndrome. We report the case of a 45-yr old man with central post-stroke pain syndrome who failed to respond to a variety of oral analgesics, but within 2 wk of the inception of gabapentin therapy, his average pain was significantly reduced and his level of function improved. We conclude that gabapentin may be an effective medication for the treatment of central post-stroke pain syndrome.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00002060-200209000-00013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Statins in Acute Ischemic Stroke: Mechanisms, Resistance, and Precision Strategies for Neurovascular and Cognitive Protection.
CNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFDiagnostic accuracy of ultrasound for dysphagia in neurological disorders including stroke: a systematic review and meta-analysis.
Front Neurol
August 2025
Department of Neurology, The First Hospital of Jilin University, Changchun, Jilin, China.
Objective: To investigate the diagnostic accuracy of ultrasonography in detecting dysphagia and to compare it with other diagnostic methods.
Methods: This is a systematic review and meta-analysis of observational studies. The literature was searched in multiple databases, including the Cochrane Central Controlled Trials Registry (a global database of controlled trials); MEDLINE, EMBASE, and Web of Science (biomedical, pharmacological, and multidisciplinary citation databases, respectively); CINAHL (focusing on nursing and allied health research); and Chinese databases including Wanfang Data, CNKI, and VIP (covering academic, scholarly, and scientific-technical literature).
Rate of Post-Stroke Depression and Associated Factors in Saudi Single Tertiary Medical Center.
J Multidiscip Healthc
September 2025
Department of Public Health, College of Health Sciences, Saudi Electronic University, Riyadh, 11673, Saudi Arabia.
Purpose: Stroke is a significant global health concern, with post-stroke depression (PSD) affecting approximately 30% of patients and contributing to reduced quality of life and increased mortality. In Saudi Arabia, data on PSD frequency and associated factors remain limited in relation to the rehabilitation of stroke patients, highlighting the need for further investigation. The study's aims to investigate the rate of PSD and the factors that influence PSD.
View Article and Find Full Text PDFCase Report: Multidimensional Analgesia via Asymmetric Dual-Target Deep Brain Stimulation of the Periaqueductal Gray and Ventral Posterior Thalamus in Central Post-stroke Pain.
Neurol Ther
September 2025
Department of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Central post-stroke pain (CPSP) is an intractable neuropathic pain syndrome. Dual-target deep brain stimulation (DBS), which integrates sensory thalamic modulation and endogenous analgesic pathways, has emerged as a potential intervention; however, clinical evidence remains scarce. We report a 54-year-old woman who developed right-sided limb paresthesia progressing to persistent right hemibody pain following a left thalamic hemorrhage.
View Article and Find Full Text PDFInterventions for post-stroke apathy and their effects: A scoping review.
Clin Rehabil
September 2025
Division of Occupational Therapy Program, Faculty of Health and Social Service, School of Rehabilitation, Kanagawa University of Human Services, Yokosuka, Japan.
ObjectiveThis scoping review aimed to comprehensively map interventions for post-stroke apathy and their effects.Data sourcesThe literature search for this review was performed using PubMed, Cumulative Index to Nursing and Allied Health Literature, and Web of Science, targeting studies published until August 7, 2025.Review methodsThis scoping review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews.
View Article and Find Full Text PDF