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Background And Purpose: Total correction of proximal hypospadias and penoscrotal transposition (PST) is a challenge to surgeons. Staged operation is usually recommended because the blood supply to the neourethra or the skin covering the penile shaft may be severed during scrotoplasty. This paper describes results obtained using a new technique for total correction, which preserves the blood supply to the neourethra in a one-stage operation.
Patients And Methods: Between July 1998 and March 2000, five boys (mean age 4 yr) with proximal hypospadias and PST underwent total correction in a one-stage operation. The urethral meatus of these patients was located at mid shaft in one, at the penoscrotal junction in two, and at the scrotum in two. Hypospadias was repaired using the Snodgrass procedure and PST was corrected using the Ehrlich and Scardino technique. Radical bulbar urethra dissection and tunica albugineal plication were used to correct penile curvature in all five cases. The urethral stent was removed on the seventh or eighth postoperative day. The meatus was then dilated using the cone tip of an ophthalmic ointment tube two or three times per day for 2 to 4 weeks. Postoperative urinary flow was observed in the outpatient clinic.
Results: The mean follow-up period was 11.2 months. There was no postoperative fistula. One patient had postoperative meatal stenosis that was successfully treated by dilation. Postoperatively, the penile base was well above the scrotal rhugae and the meatus was at the tip of the glans in each patient. The postoperative urinary flow was straight in all patients.
Conclusion: Combining Snodgrass hypospadias repair and Ehrlich and Scardino PST repair in a one-stage operation preserved the blood supply to the neourethra and achieved excellent functional and cosmetic results.
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J Pediatr Urol
August 2025
Urology Department, Pediatric Urology Section, Alexandria School of Medicine, Egypt.
Background: Hypospadias is one of the most common congenital defects of male external genitalia. Correction of severe ventral curvature remains a main challenge to surgeons. The aim of this work was to assess short term outcomes of the staged tubularized preputial graft in primary proximal hypospadias with severe ventral curvature in our center with the hypothesis that it's comparable to published results in the two stage repair technique.
View Article and Find Full Text PDFJ Urol
August 2025
School of Medicine and Public Health, The University of Newcastle, NSW, Australia.
Purpose: To assess the long-term risk of reoperation following hypospadias repair in childhood and identify the risk factors associated with reoperation. We hypothesised that the technique used to repair hypospadias would influence the re-operation rate.
Materials And Methods: Consecutive children who underwent hypospadias repair in New South Wales, Australia between 1991 and 2006 were included.
Introduction: The human skin is an important oestrogen-responsive organ containing the oestrogen receptors ERα and ERβ. Penile foreskin may have similar properties; therefore, typifying the expression and cellular location of oestrogen receptors ERα and ERβ in hypospadiac and normal foreskin can expand our knowledge of the aetiology of hypospadias.
Materials And Methods: We prospectively analysed foreskin and longitudinally excised tissue of the urethral plate of 52 male patients undergoing hypospadias repair.
Objective: To evaluate the clinical efficacy of glanular decompression and expansion surgery in repairing proximal hypospadias accompanied by hypoplastic glans penis.
Methods: Clinical data from pediatric patients with proximal hypospadias and hypoplastic glans penis admitted to the pediatric surgery department of First People's Hospital, Zunyi City from January 2020 to June 2023 were retrospectively analyzed. Patients were divided into two groups according to surgical approach: a conventional glanuloplasty group (n = 26) and a glanular decompression and expansion group (n = 28).
Biomedicines
July 2025
Department of Urology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Previously, we found that the pathological changes in the corpus spongiosum (CS) in hypospadias were mainly localized within smooth muscle tissue, presenting as a transformation from the contraction phenotype to synthesis. The role of low-intensity pulsed ultrasound (LIPUS) in regulating smooth muscle cells (SMCs) and angiogenesis has been confirmed. To demonstrate the feasibility of regulating the phenotypic transformation of corpus spongiosum smooth muscle cells (CSSMCs) in hypospadias using LIPUS and to explore the potential mechanisms.
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