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Many social, biological, and economic systems can be approached by complex networks of interacting units. In many of these systems relations are directed in the sense that links act only in one direction (outwards or inwards). We investigate the effect of directed links on the behavior of a simple spin-like model evolving on a small-world network. This model may describe for instance the dynamics of public opinion in social influence networks. We show that directed networks may lead to a highly nontrivial phase diagram including first- and second-order phase transitions out of equilibrium.
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http://dx.doi.org/10.1103/PhysRevLett.88.048701 | DOI Listing |
ACS Nano
September 2025
Department of Chemical Physics, Key Laboratory of Precision and Intelligent Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
The coupling between transition metal dichalcogenides (TMDCs) and SrTiO has recently emerged as a fertile platform for discovering interfacial phenomena, where particle interactions, lattice coupling, and dielectric screening give rise to interesting physical effects. These hybrid systems hold significant promise for two-dimensional (2D) electronics, ferroelectric state control, and metastable phase engineering. However, effective modulation of the interfacial electronic structure remains a critical challenge.
View Article and Find Full Text PDFStroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFAnim Sci J
September 2025
Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.
The aims of this study were to investigate the effects of re-vitrification at the pronuclear (PN) stage of porcine embryos generated from vitrified oocytes on subsequent development and to clarify if re-vitrification is more feasible at the PN stage or at the blastocyst stage. Immature porcine oocytes at the germinal vesicle (GV) stage were vitrified/warmed and subjected to in vitro maturation, parthenogenetic activation (PA), and embryo culture. Subsequent parthenotes were either cultured without re-vitrification for 6 days (GV-vit group) or were re-vitrified 8 h after PA at the PN stage (GV-vit/PN-revit group), and after warming, cultured for 6 days.
View Article and Find Full Text PDFCNS Neurosci Ther
September 2025
Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Aims: Sustained neuroinflammation following ischemic stroke impedes post-injury tissue repairment and neurological functional recovery. Developing innovative therapeutic strategies that simultaneously suppress detrimental inflammatory cascades and facilitate neurorestorative processes is critical for improving long-term rehabilitation outcomes.
Methods: We employed a microglia depletion-repopulation paradigm by administering PLX5622 for 7 days post-ischemia; followed by a 7-day withdrawal period to allow microglia repopulation.
Biophys J
September 2025
Laboratory for Multiscale Mechanics and Medical Science, State Key Laboratory for Strength and Vibration of Mechanical Structures, School of Aerospace Engineering, Xi'an Jiaotong University, Xi'an, 710049, China. Electronic address:
The mechanical properties of cells are crucial for elucidating various physiological and pathological processes. Cells are found to exhibit a universal power-law rheological behavior at low frequencies. While they behave in a different manner at high frequency regimes, which leaves the transition region largely unexplored.
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