Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Diarylpiperidines (8-12) may be prepared in good to excellent yields (80-99%) by the reaction of piperidones (3d-h) with benzene and the Bronsted superacid, trifluoromethanesulfonic acid (CF(3)SO(3)H, TfOH). Tropinone (6) and quinuclidone (7) also react in good yields with benzene in TfOH to give the condensation products (13 and 14). Ketal and acetal derivatives also give condensation products (8 and 24) upon reaction with C(6)H(6) in TfOH. The conversion of 3g to 11 is sensitive to both acid quantity and acid strength; a mechanism is proposed for the conversion that invokes dicationic intermediates.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jo990454i | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dual sulfur sources redox dynamics guided growth of 〈hk1〉-oriented SbS microrods: lattice strain modulation for ultra-low dark current.
J Colloid Interface Sci
September 2025
College of Physics and Electronic Information, Yunnan Key Laboratory of Optoelectronic Information Technology, Yunnan Normal University, Kunming 650500, China. Electronic address:
Antimony trisulfide (SbS) has emerged as a promising inorganic semiconductor for optoelectronics due to its distinctive anisotropic crystal structure and suitable bandgap (∼1.7 eV). While hydrothermal synthesis remains challenging for achieving high crystallinity and controlled morphology, we developed an innovative dual‑sulfur precursor strategy utilizing sodium thiosulfate (STS) and thioacetamide (TAA) at a 7:2 M ratio with SbCl.
View Article and Find Full Text PDFIn-depth investigation of the spatial variations of DOM components in sediments under the influence of cascade dams and their interactions with microbial communities.
J Environ Manage
September 2025
Key Lab of Basin Water Resource and Eco-Environmental Science in Hubei Province, Basin Water Environmental Research Department, Changjiang River Scientific Research Institute, No.23 Huangpu Road, Wuhan, 430010, PR China; Innovation Team for Basin Water Environmental Protection and Governance of Chan
Small cascade dams drive spatial divergence in the composition of dissolved organic matter (DOM) in local sediments. Taking Xixi River in the southeast of China, a representative small cascade-dammed watershed, as an example, this study explored the spatial variations of DOM components and its interactions with microbial communities under the influence of cascade dams. Results revealed that DOM composition differed significantly, i.
View Article and Find Full Text PDFUnveiling the role of biomolecular condensates in cellular function and cancer.
Adv Biol Regul
September 2025
Laboratory of Cancer Cell Architecture, Institute of Biochemistry and Experimental Oncology, First Faculty of Medicine, Charles University, Prague, Czech Republic. Electronic address:
Biomolecular condensates (BMCs) are membrane-less organelles formed through liquid-liquid phase separation, primarily driven by multivalent interactions between scaffold and client molecules. These dynamic compartments enable cells to spatially and temporally organize biochemical reactions by locally concentrating specific biomolecules, thereby enhancing the frequency of productive molecular interactions and increasing reaction rates. BMCs are integral to normal cellular physiology, with well-characterized examples including the nucleolus and Cajal bodies.
View Article and Find Full Text PDFMolecular-level insights into directional condensation mechanism of phenolic acids during humic substance formation.
Bioresour Technol
September 2025
Tianjin Key Laboratory of Animal and Plant Resistance, College of Life Sciences, Tianjin Normal University, Tianjin 300387, China. Electronic address:
The regulation of humic substance formation during aerobic fermentation of organic solid waste has gradually become a research hotspot in related fields. The metabolic byproducts of lignocellulose have the potential to act as precursors for the synthesis of humic substances. This study, grounded in a robust framework of metabolic intermediate indicators, selected representative pure phenolic acid intermediates to conduct condensation experiments.
View Article and Find Full Text PDFReactive Molecular Dynamics Study on the Growth Mechanism of Nitrogen-Doped Graphene in an Arc Plasma Environment.
J Mol Model
September 2025
School of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, 350116, People's Republic of China.
Context: This study systematically investigates the growth mechanism of nitrogen-doped graphene in a plasma environment, with a particular focus on the effects of temperature and hydrogen radicals on its structural evolution. The results reveal that, at 3000 K, the formation of nitrogen-doped graphene proceeds through three stages: carbon chain elongation, cyclization, and subsequent condensation into planar structures. During this process, nitrogen atoms are gradually incorporated into the carbon network, forming various doping configurations such as pyridinic-N, pyrrolic-N, and graphitic-N.
View Article and Find Full Text PDF