Effects of mindfulness yoga during pregnancy on psychological and pregnancy outcomes in multiparous women of advanced maternal age.

Background: Multiparous women of advanced maternal age are more susceptible to psychological stress.

Objective: This study examined the impact of mindfulness yoga on psychological well-being (anxiety and sleep quality) and pregnancy outcomes (Apgar scores and adverse perinatal events) in aging multiparous women.

Study Design: Participants meeting the criteria were randomly assigned to a control or a mindfulness yoga intervention group.

The role of MUC16 in tumor biology and tumor immunology in ovarian cancer.

In this study, the influence of glycoproteomic changes, specifically MUC16, on NK cell-mediated immunotherapy response in ovarian cancer is explored. Analysis of glycoprotein data from the CPTAC database identified significant upregulation of MUC16 in ovarian cancer tissues, associated with tumor invasiveness and immune evasion. Experimental findings showed that MUC16 knockdown increased NK cell cytotoxicity, decreased invasiveness, and boosted NK cell activation, while MUC16 overexpression resulted in the opposite effects.

Intravenous iron therapy for treating patients with iron deficiency anaemia during the perioperative period of gynecological malignancy.

Anaemia is a common phenomenon in patients with malignant gynecological tumors. The occurrence of anaemia in the perioperative period leads to an increased probability of blood transfusion, increased surgical complications,poor wound healing, prolonged hospitalization, increased medical costs, and increased mortality. Intravenous iron, which is known for its rapid onset and lack of gastrointestinal side effects, has become increasingly prevalent in clinical practice.