Organic Cage Encapsulated Within Metal Cluster-Based Open Frameworks: A Single-Crystal Host-in-Host Material with Inter-Host Charge Cooperation.

Integrating dissimilar building units of discrete organic cages and inorganic clusters into single-crystal supramolecular frameworks with tailored architectures and synergistic functions presents a significant challenge. Here, we presented our discovery of achieving such hybrids through electrostatically driven self-assembly of cationic ammonium organic cages with anionic lead iodide clusters. Notably, by carefully modulating the size, shape, and composition of cationic organic cages, we have constructed an integrated porous host-in-host architecture.

A Series of Rare-Earth Metal-Based Coordination Polymers: Fluorescence and Sensing Studies.

Ratiometric fluorescent sensing based on dual-emitting fluorescent coordination polymers (FL-CPs) has attracted intense attention due to their sensing accuracy and easy visualization when compared with sensing relying solely on monochromatic FL-CPs. In this work, a series of rare-earth metal-based CPs, formuled as [(CH)NH][Ln(bpdc)] (Ln = Y, Eu and Tb, Hbpdc = biphenyl-4,4'-dicarboxylic acid), are presented, which show dual emission aroused from the Ln ions and the inefficient intermolecular energy transfer from ligands to Ln metals. For clarity, the as-made Ln-CPs are named Eu-bpdc, Tb-bpdc, and Y-bpdc based on the corresponding Ln.

TMB Signature-Related RCAN2 Promotes Apoptosis by Upregulating EHF/DR5 Pathway in Hepatocellular Carcinoma.

Background: The tumour mutation burden (TMB) is a valuable indicator of the accumulation of somatic mutations, and is thought to be associated with the biological behaviour and prognosis of tumours. However, the related genetic mechanism for these association is still unclear. The aim of the present study was to identify the key gene(s) associated with TMB in hepatocellular carcinoma (HCC) and to investigate its biological functions, downstream transcription factors, and mechanism of action.

Correction: The {CuI} cluster bearing metal organic frameworks: crystal structures and fluorescence detecting performances towards cysteine and explosive molecules.

Correction for 'The {CuI} cluster bearing metal organic frameworks: crystal structures and fluorescence detecting performances towards cysteine and explosive molecules' by Jiang Jiang , , 2024, , 706-714, https://doi.org/10.1039/d3dt03363e.

Confinement of 1D Chain and 2D Layered CuI Modules in K-INA-R Frameworks via Coordination Assembly: Structure Regulation and Semiconductivity Tuning.

Herein, we present a new series of CuI-based hybrid materials with tunable structures and semiconducting properties. The CuI inorganic modules can be tailored into a one-dimensional (1D) chain and two-dimensional (2D) layer and confined/stabilized in coordination frameworks of potassium isonicotinic acid (HINA) and its derivatives (HINA-R, R = OH, NO, and COOH). The resulting CuI-based hybrid materials exhibit interesting semiconducting behaviors associated with the dimensionality of the inorganic module; for instance, the structures containing the 2D-CuI module demonstrate significantly enhanced photoconductivity with a maximum increase of five orders of magnitude compared to that of the structures containing the 1D-CuI module.

Confinement of Pyridine Derivatives into a Metal-Organic Framework Host as Electron Acceptors to Achieve Photoinduced Electron-Transfer.

The photoinduced electron-transfer (ET) process plays an irreplaceable role in chemical and biological fields exemplified by enzymatic catalysis, artificial photosystems, solar energy conversion, and so forth. Searching for a new photoinduced ET system is of great importance for the development of functional materials. Herein, a series of host-guest compounds based on a magnesium metal-organic framework (Mg-MOF) as a host and pyridine derivatives as guests have been presented.

A Cerium Organic Framework with {CuI} Cluster and {CuI} Chain Modules: Structure and Fluorescence Sensing Properties.

In this work, a copper iodine module bearing a coordination polymer (CP) with a formula of [(CuI)Ce(INA)(DMF)]·DMF (, HINA = isonicotinic acid, DMF = ,-dimethyl formamide) is presented. The title compound features a three dimensional (3D) structure, in which the {CuI} cluster and {CuI} chain modules are coordinated by N atoms from a pyridine ring in INA ligands, while the Ce ions are bridged by the carboxylic groups of INA ligands. More importantly, compound exhibits an uncommon red fluorescence (FL) with a single emission band maximized at 650 nm belonging to near infrared (NIR) luminescence.

A Robust Strontium Coordination Polymer with Selective and Sensitive Fluorescence Sensing Ability for Fe Ions.

Exploration of sensitive and selective fluorescence sensors towards toxic metal species is of great importance to solve metal pollution issues. In this work, a three-dimensional (3D) strontium coordination polymer of Sr(tcbpe) (Htcbpe = 1,1,2,2-tetrakis(4-(4-carboxy-phenyl)phenyl)ethene) has been synthesized and developed as a fluorescent sensor to Fe ions. Sr(tcbpe) shows a mechanochromic fluorescence with emission shifting from blue of the pristine to green after being ground.

Single-Crystal Superstructures via Hierarchical Assemblies of Giant Rubik's Cubes as Tertiary Building Units.

Intricate superstructures possess unusual structural features and promising applications. The preparation of superstructures with single-crystalline nature are conducive to understanding the structure-property relationship, however, remains an intriguing challenge. Herein we put forward a new hierarchical assembly strategy towards rational and precise construction of intricate single-crystal superstructures.

An Iron-NDC Framework with a Cage Structure and an Optothermal Conversion in NIR Window.

Pursuing novel materials with efficient photothermal conversion under irradiation at the near-infrared region windows (NIR, 750-850 nm; NIR-I and NIR-II, 1000-1320 nm)) is of great importance due to their irreplaceable applications, especially in the biomedical field. Herein, on the basis of a coordination chemistry strategy, an iron-based metal-organic framework (MOF) of [N(CH)][Fe(NDC)]·DMF·3HO (, 1,4-HNDC = 1,4-naphthalenedicarboxylic acid, N(CH) = tetramethyl-ammonium, and DMF = N,N-dimethylformamide) was prepared and characterized. Due to the - transition effect introduced by coordination with the transition-metal ion of iron and the highly conjugated naphthalenic moiety in 1,4-HNDC, guaranteeing an energy transfer between iron and the organic module, shows a remarkable broad absorption, which could be extended into the NIR-II section.

Achieving a blue-excitable yellow-emitting Ca-LMOF phosphor water induced phase transformation.

Luminescent metal-organic frameworks (LMOFs) with diverse structural features and promising fluorescence-based applications have attracted wide attention in the past two decades. In this work, a LMOF with the formula [Ca(tcbpe-F)(HO)] (1, LMOF-411) has been constructed from calcium (Ca) and 1,1,2,2-tetrakis(4-(4-carboxyphenyl)phenyl)ethene (Htcbpe-F). Compound 1 features a three-dimensional framework with a 10-nodal net topology.

[BaSbClO]: high-nuclearity cluster for the assembly of nanocluster-based compounds.

Herein, we report two nanocluster-based compounds built on an unprecedented cluster [BaSbClO], which represents the first example of a discrete alkaline earth (AE)-containing oxochloride cluster and the largest Sb-based oxohalide cluster to date; the proton-conducting property of the compounds was investigated.

Effects of interleukin-7/interleukin-7 receptor on RANKL-mediated osteoclast differentiation and ovariectomy-induced bone loss by regulating c-Fos/c-Jun pathway.

To explore the effects of IL-7/IL-7R on the RANKL-mediated osteoclast differentiation in vitro and OVX-induced bone loss in vivo. BMMs and RAW264.7 were transfected with IL-7, IL-7R siRNA, c-Fos siRNA, and c-jun siRNA and later stimulated by RANKL.

Mg incorporated Co-based MOF precursors for hierarchical CNT-containing porous carbons with ORR activity.

In this paper, we introduced light and abundant metal magnesium into a cobalt-based metal organic framework (Co-MOF, [(CH)NH][Co(bpdc)]·5DMF·4CHOH) (1, Hbpdc = 4,4'-biphenyldicarboxylic acid, DMF = N,N-dimethylformamide) as a heteroatom to synthesize Mg-Co bimetallic MOFs, namely [(CH)NH][MgCo(bpdc)]·4DMF·5CHOH (2) and [(CH)NH][MgCo(bpdc)] 4DMF·4CHOH·6HO (3). Based on the formation of a rather low density framework after the introduction of the light Mg, such bimetallic MOFs exhibited higher gas adsorption abilities than the isostructural Co-based MOF 1. N adsorption measurements demonstrate that the BET surface area of 3 is 305.

A series of Mg-Zn heterometallic coordination polymers: synthesis, characterization, and fluorescence sensing for Fe, CS, and nitroaromatic compounds.

Herein, the solvothermal preparations, crystal structures, and fluorescence properties of three Mg-Zn heterometallic coordination polymers (CPs), i.e. [MgZn(OH)(1,4-NDC)(HO)]·6HO (1), [MgZn(1,4-NDC)(dppe)(CHOH)] (2), and [MgZn(1,4-NDC)(py)]·1.

Fine decoration of carbon nanotubes with metal organic frameworks for enhanced performance in supercapacitance and oxygen reduction reaction.

Efficient electrode material is crucial for energy conversion from renewable sources such as solar electricity. We present a method for preparation of carbon nanotubes (CNTs) with zeolitic imidazolate frameworks (ZIFs, e.g.

A Mg-CP with in Situ Encapsulated Photochromic Guest as Sensitive Fluorescence Sensor for Fe/Cr Ions and Nitro-Explosives.

Here we report a fluorescent magnesium coordination polymer (Mg-CP), namely, [CH-dpb][Mg(1,4-NDC)(μ-HO)(CHOH)(HO)]·1.5HO (1, 1,4-HNDC = 1,4-naphthalene dicarboxylic acid, dpb = 1,4-bis(pyrid-4-yl)benzene). Compound 1 possesses a three-dimensional (3D) host-guest structure constructed by the 1,4-NDC linkers bridging the linear trinuclear secondary building units of [Mg(COO)(μ-HO)].

MicroRNA-145 Mediates Steroid-Induced Necrosis of the Femoral Head by Targeting the OPG/RANK/RANKL Signaling Pathway.

Objective: To investigate the role of microRNA-145 (miR-145) in steroid-induced necrosis of the femoral head (SINFH) by evaluating its effects on the OPG/RANK/RANKL signaling pathway.

Methods: A rat model of SINFH was constructed via injection of the lentiviral vector pLV-shRNA-miR-145. Pathological observation was performed via tartrate-resistant acid phosphatase (TRAP) staining, and serum OPG levels were detected by ELISA.

Dual-Emission Luminescence of Magnesium Coordination Polymers Based on Mixed Organic Ligands.

Presented herein are two luminescent magnesium coordination polymers (Mg-CPs), namely [Mg2 (H2O)2 (2-NDC)4 (1,10-phen)2] (1) and [Mg2 (H2O)(1,4-NDC)2 (1,10-phen)] (2), in which 2-NDCH=2-naphthalenecarboxylic acid, 1,4-NDCH2 =1,4-naphthalene dicarboxylic acid, and 1,10-phen=1,10-phenanthroline. Based on the mixed ligands, the title compounds exhibit linker-based photoluminescence (PL) properties thanks to the unique configuration of the Mg(2+) ions. The two compounds show interesting dual emission on excitation of the different luminophores of the mixed linkers.

Tunable photoluminescence and direct white-light emission in Mg-based coordination networks.

The bpy, dpe and dppe were introduced as auxiliary ligands, respectively, to construct three magnesium-1,4-NDC coordination polymers (Mg-CPs) that exhibited tunable photoluminescence (PL) and direct white-light emission upon varying the excitation light.

Small interfering RNA (siRNA)-mediated knockdown of macrophage migration inhibitory factor (MIF) suppressed cyclin D1 expression and hepatocellular carcinoma cell proliferation.

Macrophage migration inhibitory factor (MIF), a proinflammatory and immunoregulatory chemokine, plays important roles in cancer-related biological processes. However, few studies have focused on the clinical relevance of MIF and cyclin D1 expression in hepatocellular carcinoma cells (HCCs). In this study, MIF and cyclin D1 expression levels in HCC tissues and cell lines were significantly upregulated compared with adjacent normal tissues or a normal liver cell line.

The effect of microdosimetric 12C6+ heavy ion irradiation and Mg2+ on canthaxanthin production in a novel strain of Dietzia natronolimnaea.

Background: Dietzia natronolimnaea is one of the most important bacterial bioresources for high efficiency canthaxanthin production. It produces the robust and stable pigment canthaxanthin, which is of special interest for the development of integrated biorefineries. Mutagenesis employing 12C6+ irradiation is a novel technique commonly used to improve microorganism productivity.

Ionothermal syntheses, crystal structures and properties of three-dimensional rare earth metal-organic frameworks with 1,4-naphthalenedicarboxylic acid.

Twelve isostructural rare earth metal-organic frameworks, namely, [Hmim][RE(2)Cl(1,4-NDC)(3)] (RE = La (1), Ce (2), Pr (3), Nd (4), Sm (5), Eu (6), Gd (7), Tb (8), Dy (9), Ho (10), Er (11), Y (12), Hmim = 1-hexyl-3-methylimidazolium, 1,4-NDCH(2) = 1,4-naphthalenedicarboxylic acid), have been ionothermally synthesized and structurally characterized. The structures feature three-dimensionally anionic frameworks of [RE(2)Cl(1,4-NDC)(3)](n)(n-) with channels in which the Hmim(+) cations are located. The current results are the first ionothermal synthesis of rare earth metal-organic frameworks based on 1,4-NDCH(2) which possess a previously unknown (4,7)-connected 3-nodal network with the Schläfli symbol of (3(2)·4(2)·5(2))(3(2)·4(9)·5(2)·6(8))(2)(4(3)·6(3))(2).