Publications by authors named "Zachary A Cupler"

Introduction: Research suggests that migraine without aura (MwoA) is a risk factor for cervical artery dissection (CeAD); however, the association between migraine with aura (MwA) and CeAD remains inconclusive. We tested the coprimary hypotheses of positive associations between both MwA and MwoA and CeAD within two years following migraine diagnosis, compared to matched non-migraine controls, as measured by risk ratio (RR).

Methods: We queried de-identified US medical records data (TriNetX, LLC, Cambridge, Massachusetts, United States) spanning the years 2014-2024 to identify three cohorts of patients without previous CeAD.

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Background: Physicians, allied health clinicians, scientists, and industry partners' use of social media has grown exponentially, permeating across all levels of healthcare delivery and practice. Spine care professionals can interact with both professional and patient audiences across social media platforms.

Methods: This article aims to narratively outline social media best practices for the spine care professional.

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Background: Surgical intervention for lumbar spinal stenosis (LSS) is common and associated with high rates of postoperative side effects or complications. Prehabilitation programs aim to reduce postoperative complications and enhance outcomes. However, the clinical effectiveness of prehabilitation programs for patients undergoing LSS surgery has yet to be fully investigated.

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Background Context: The North American Spine Society's (NASS) Evidence-Based Clinical Guideline for the Diagnosis and Treatment of Adults with Neoplastic Vertebral Fractures features evidence-based recommendations for diagnosing and treating adult patients with neoplastic vertebral fractures. The guideline is intended to reflect contemporary treatment concepts for neoplastic vertebral fractures as reflected in the highest quality clinical literature available on this subject as of October 2020.

Purpose: The purpose of the guideline is to provide an evidence-based educational tool to assist spine specialists when making clinical decisions for adult patients with neoplastic vertebral fractures.

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Background Context: The North American Spine Society's (NASS) Evidence-Based Clinical Guideline for the Diagnosis and Treatment of Adults with Osteoporotic Vertebral Compression Fractures features evidence-based recommendations for diagnosing and treating adult patients with osteoporotic vertebral compression fractures. The guideline is intended to reflect contemporary treatment concepts for osteoporotic vertebral compression fractures as reflected in the highest quality clinical literature available on this subject as of September 2020.

Purpose: The purpose of the guideline is to provide an evidence-based educational tool to assist spine specialists when making clinical decisions for adult patients with osteoporotic vertebral compression fractures.

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Background: Patients receiving chiropractic spinal manipulation (CSM) for spinal pain are less likely to be prescribed opioids, and some evidence suggests that these patients have a lower risk of any type of adverse drug event. We hypothesize that adults receiving CSM for sciatica will have a reduced risk of opioid-related adverse drug events (ORADEs) over a one-year follow-up compared to matched controls not receiving CSM.

Methods: We searched a United States (US) claims-based data resource (Diamond Network, TriNetX, Inc.

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Article Synopsis
  • * Researchers performed a systematic review to identify and refine competencies, resulting in 78 agreement statements across four main domains: Collaboration, Clinical Excellence, Communication, and Systems Administration.
  • * The findings aim to guide chiropractic education programs in developing curricula that prepare students for careers in integrated healthcare, ultimately enhancing their employability and effectiveness in clinical practice.
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Objectives: Patients receiving chiropractic spinal manipulation (CSM) for low back pain (LBP) are less likely to receive any opioid prescription for subsequent pain management. However, the likelihood of specifically being prescribed tramadol, a less potent opioid, has not been explored. We hypothesised that adults receiving CSM for newly diagnosed radicular LBP would be less likely to receive a tramadol prescription over 1-year follow-up, compared with those receiving usual medical care.

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Introduction: Lumbar spinal stenosis (LSS) is a leading cause of chronic musculoskeletal pain among older adults. A common and costly intervention for the treatment of LSS is lumbar decompression with or without fusion (LSS surgery), which has mixed outcomes among patients. Prehabilitation is a strategy designed to optimize the consistency of positive surgical outcomes and promote patient self-efficacy, while attempting to mitigate postoperative complications.

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Background Case reports have raised the possibility of an association between coronavirus disease 2019 (COVID-19) and spontaneous cervical artery dissection (sCeAD), yet no large studies have examined this association. We hypothesized that adults with confirmed COVID-19 would have an increased risk of sCeAD over the subsequent six months compared to test-negative controls after adjusting for confounding variables. Methods We obtained data from a United States medical records network (TriNetX, Inc.

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Article Synopsis
  • The study aims to explore the ideologies, beliefs, and practice patterns of chiropractors in the US, focusing on three distinct subgroups based on their areas of practice: spine/neuromusculoskeletal, primary care, and vertebral subluxation.
  • It employs a secondary analysis of a cross-sectional survey conducted over nearly two years, capturing data from a random sample of 8,975 licensed chiropractors across all states and the District of Columbia.
  • The analysis examines how factors such as chiropractic degree program, years since graduation, and geographic region influence the chiropractors' responses to various survey items related to their ideologies, health treatment roles, and practices.
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Objectives: Radicular low back pain (rLBP) is often treated off-label with gabapentin or by chiropractors using chiropractic spinal manipulative therapy (CSMT). To date, no studies have examined the association between these interventions. We hypothesised that adults under 50 years of age receiving CSMT for newly diagnosed rLBP would have reduced odds of receiving a gabapentin prescription over 1 year-follow-up.

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Objective: The primary objective of this study was to assess, summarize, and compare the current integrated clinical learning opportunities offered for students who matriculated in US doctor of chiropractic programs (DCPs).

Methods: Two authors independently searched all accredited DCP handbooks and websites for clinical training opportunities within integrated settings. The 2 data sets were compared with any discrepancies resolved through discussion.

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Objectives: Although chiropractic spinal manipulative therapy (CSMT) and prescription benzodiazepines are common treatments for radicular low back pain (rLBP), no research has examined the relationship between these interventions. We hypothesise that utilisation of CSMT for newly diagnosed rLBP is associated with reduced odds of benzodiazepine prescription through 12 months' follow-up.

Design: Retrospective cohort study.

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Objective: To identify and descriptively compare medication recommendations among low back pain (LBP) clinical practice guidelines (CPG).

Methods: We searched PubMed, Cochrane Database of Systematic Review, Index to Chiropractic Literature, AMED, CINAHL, and PEDro to identify CPGs that described the management of mechanical LBP in the prior five years. Two investigators independently screened titles and abstracts and potentially relevant full text were considered for eligibility.

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Article Synopsis
  • Cervical spine surgeries for degenerative conditions are increasing, leading to common issues like chronic pain and recurrent problems, prompting some patients to seek manual therapy, although guidelines for its use post-surgery are lacking.
  • This study reviewed literature from various databases to assess outcomes of manual therapy in adults who had prior cervical spine surgeries, focusing on randomized clinical trials and case reports.
  • The review identified twelve articles, mostly case reports, with limited evidence from clinical trials, highlighting mixed outcomes related to manual therapy interventions in patients having undergone various cervical spine surgeries.
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Background And Purpose: Pain and disability may persist following lumbar spine surgery and patients may subsequently seek providers trained in manipulative and manual therapy (MMT). This systematic review investigates the effectiveness of MMT after lumbar surgery through identifying, summarizing, assessing quality, and grading the strength of available evidence. Secondarily, we synthesized the impact on medication utilization, and reports on adverse events.

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