Publications by authors named "Yunho Jung"

Background And Aims: Colonic stenting using self-expandable metallic stents (SEMS) as a bridge to surgery offers an effective alternative to emergency surgery for the management of malignant colorectal obstruction. However, the optimal timing of elective surgery after stenting remains controversial.

Methods: This retrospective multicenter cohort study analyzed 380 patients with obstructive colorectal cancer who were treated with SEMS as a bridge to surgery.

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Crohn's disease (CD) is a chronic inflammatory disorder with potential progression to stricturing (B2) or penetrating (B3) phenotypes, leading to significant complications. Early identification of patients at risk for these complications is critical for personalized management. This study aimed to develop a predictive model using clinical data and a Korean-specific transcriptome-wide association study (TWAS) to forecast early progression in CD patients.

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Background And Aims: Self-expandable metal stents (SEMS) are effective in alleviating malignant colorectal obstruction. However, bowel perforation following SEMS placement remains a significant concern, as it can adversely affect oncological outcomes. This study aimed to evaluate the recurrence and overall survival rates associated with SEMS-related bowel perforations.

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Background/aims: We investigated the clinical practice patterns of Korean endoscopists for the endoscopic resection of colorectal polyps.

Methods: From September to November 2021, an online survey was conducted regarding the preferred resection methods for colorectal polyps, and responses were compared with the international guidelines.

Results: Among 246 respondents, those with <4 years, 4-9 years, and ≥10 years of experience in colonoscopy practices accounted for 25.

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Background: Oral sulfate tablets (OSTs) are bowel preparation agents that combine oral sulfate solution and simethicone. This study compared the efficacy, tolerability, and safety of OST compared to 2 L-polyethylene glycol plus ascorbic acid (2 L-PEG/ASC).

Methods: This prospective, randomized, controlled, single-blinded, multicenter, noninferiority trial enrolled 211 healthy adults who underwent colonoscopy between May 2020 and September 2022 at 13 university hospitals.

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Article Synopsis
  • Early colorectal cancer (ECC) is often treated with endoscopic resection, which can sometimes lead to perforations, a serious complication.
  • A study of 965 patients found that specific techniques, like endoscopic submucosal dissection, significantly increase the risk of perforation during these procedures.
  • Interestingly, while perforations occurred in 3.4% of cases, they did not affect patient survival, indicating that the type of resection performed is a key factor in risk assessment.
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Background And Aims: Polypectomy is a procedure associated with a high risk of bleeding. Guidelines recommend uninterrupted aspirin use during polypectomy, whereas cessation of clopidogrel 5 to 7 days before polypectomy is recommended. The cold snare resection (CSR) technique, with or without submucosal injection, is considered safer than conventional polypectomy using electrocoagulation for postpolypectomy bleeding.

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Colonoscopy has a limited field of view because it relies solely on a small camera attached to the end of the scope and a screen displayed on a monitor. Consequently, the quality and safety of diagnosis and treatment depend on the experience and skills of the gastroenterologist. When a novice attempts to insert the colonoscope during the procedure, excessive pressure can sometimes be applied to the colon wall.

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The risk factors for immediate post-polypectomy bleeding (IPPB) after cold snare polypectomy (CSP) are not well-known. We sought to define such risk factors and develop a predictive risk-scoring model. This prospective observational study included 161 polyps (4-9 mm in diameter) that were removed via CSP from 118 patients during the period from June to September 2019 in 2 tertiary hospitals.

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Article Synopsis
  • The study assessed the safety and effectiveness of ustekinumab (UST) in treating Korean patients with Crohn's disease over a four-year period, gathering data from 464 patients across 44 hospitals.
  • Results showed that clinical response rates were high at first (75% by week 20) but decreased by week 66 (62.4%), with higher success rates in patients who had not previously used biologics.
  • Adverse events occurred in 28.2% of patients, but no new safety concerns were identified, suggesting UST is generally safe and beneficial for this demographic.
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Article Synopsis
  • - Significant advances in managing large laterally spreading tumors (LSTs) in colorectal polyps exist, but management practices vary globally, prompting the need for an international consensus.
  • - A Delphi study involving 43 experts from 18 countries led to 42 statements reaching consensus regarding training, evaluation, resection techniques, and post-resection care for LSTs.
  • - The resulting expert consensus aims to standardize practices and provide clear guidance for evaluating, resecting, and following up on LSTs worldwide.
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The detection of early colorectal cancer (CRC) is increasing through the implementation of screening programs. This increased detection enhances the likelihood of minimally invasive surgery and significantly lowers the risk of recurrence, thereby improving patient survival and reducing mortality rates. T1 CRC, the earliest stage, is treated endoscopically in cases with a low risk of lymph node metastasis (LNM).

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  • A study analyzed how Korean endoscopists manage post-polypectomy colonoscopy surveillance, focusing on their preferred intervals and when to stop surveillance based on survey responses.
  • The survey, conducted with 196 endoscopists, found varying surveillance recommendations depending on the type and quantity of polyps removed, with many preferring a 1-year to 5-year interval based on specific cases.
  • Only about 30.7% of respondents adhered to the latest US guidelines, indicating a need for more individualized approaches to improve compliance.
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Background/aim: We aimed to validate clinical decision support tools (CDSTs) to predict real-life effectiveness of vedolizumab (VDZ) in patients with inflammatory bowel disease.

Methods: We retrospectively enrolled patients with Crohn's disease (CD) or ulcerative colitis (UC) treated with VDZ at 10 tertiary referral centres in Korea between January 2017 and November 2021. We assessed clinical remission (CREM) and response (CRES), corticosteroid-free clinical remission (CSF-CREM) and response (CSF-CRES), biochemical response based on C-reactive protein (BioRES[CRP]) and faecal calprotectin (BioRES[FC]), endoscopic healing (EH), and the need to optimise or switch drugs based on CDST-defined response groups.

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Sensor applications in internet of things (IoT) systems, coupled with artificial intelligence (AI) technology, are becoming an increasingly significant part of modern life. For low-latency AI computation in IoT systems, there is a growing preference for edge-based computing over cloud-based alternatives. The restricted coulomb energy neural network (RCE-NN) is a machine learning algorithm well-suited for implementation on edge devices due to its simple learning and recognition scheme.

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Background: We compared the efficacy, tolerability, and safety of oral sulfate tablets (OST, which contains simethicone) and 2 L-polyethylene glycol/ascorbate (2 L-PEG/Asc) with a split-dosing regimen in older individuals aged ≥ 70 years who underwent scheduled colonoscopy.

Methods: This prospective, randomized, investigator-blinded, multicenter study was conducted between June 2022 and October 2023. Participants aged ≥ 70 years were randomized at a ratio of 1:1 to the OST or 2 L-PEG/Asc groups.

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Hand gesture recognition, which is one of the fields of human-computer interaction (HCI) research, extracts the user's pattern using sensors. Radio detection and ranging (RADAR) sensors are robust under severe environments and convenient to use for hand gestures. The existing studies mostly adopted continuous-wave (CW) radar, which only shows a good performance at a fixed distance, which is due to its limitation of not seeing the distance.

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This paper addresses the challenge of enhancing range precision in radar sensors through supervised learning. However, when the range precision surpasses the range resolution, it leads to a rapid increase in the number of labels, resulting in elevated learning costs. The removal of background noise in indoor environments is also crucial.

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Article Synopsis
  • Colorectal endoscopic submucosal dissection (ESD) was studied to compare outcomes for tumors sized 15-19 mm versus larger tumors (≥ 20 mm).
  • The study involved 213 colorectal tumor cases, showing that ESD for 15-19 mm tumors had a higher en bloc resection rate (100% vs. 94%) and a shorter average total procedure time compared to larger tumors.
  • Although the procedure speed was slower for the 15-19 mm group, both groups had similar rates of complete resection and complications, indicating that ESD for smaller lesions is effective and efficient.
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Keyword spotting (KWS) systems are used for human-machine communications in various applications. In many cases, KWS involves a combination of wake-up-word (WUW) recognition for device activation and voice command classification tasks. These tasks present a challenge for embedded systems due to the complexity of deep learning algorithms and the need for optimized networks for each application.

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Background/aims: This study investigated whether the personality traits of endoscopists are associated with the effect of interventions for the improvement of colonoscopy quality.

Methods: This prospective, multicenter, single-blind study was performed with 13 endoscopists in three health screening centers over a 12-month period. Quality indicators (QIs), including adenoma detection rate (ADR), polyp detection rate (PDR), and withdrawal time, were measured every 3 months.

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