Probing the Evolution of Single-Shelled TiO Hollow Microspheres by Electrochemiluminescence.

The evolution of single-shelled hollow microspheres is crucial for understanding their structures and advanced applications in catalysis, sensing, and energy conversion. In this work, we employed electrochemiluminescence (ECL) to track the formation process of single-shelled titanium dioxide hollow microspheres (1S-TiO-HMS) synthesized via a carbon microsphere-templated method with controlled calcination times. As calcination progressed, the ECL intensity of a tris(2,2'-bipyridine)ruthenium(II) (Ru(bpy))-tri--propylamine (TPA) system continuously increased with the decomposed carbon microsphere template and the assembly of TiO nanoparticles into an ordered shell.

Real-Time Monitoring Supramolecular Disassembly by Nanoconfinement Engineering-Tuned Electrochemiluminescence.

Understanding the disassembly process is significant for constructing well-defined and multifunctional supramolecular structures. Nowadays, fluorescent microscopy is used as a common technique to observe a real-time disassembly process. However, the addition of the fluorescent probes into nonfluorescent systems might influence the disassembly due to the weak supramolecular interactions.

Differentiating Molecular Weights of Supramolecular Polymers in Lower Monomer Concentrations by Coreaction Accelerator-Regulated Electrochemiluminescence.

Nuclear magnetic resonance is the most conventional approach to characterizing the molecular weight () of supramolecular polymers (SPs) at high monomer concentrations. However, it remains a great challenge to determine SPs with lower values because the increased monomer concentrations will assemble dynamically to larger SPs. In this contribution, we developed an SP-regulated electrochemiluminescence (ECL) strategy for differentiating the of SPs in low monomer concentrations.

Sulfonic Acid-Functionalized Tetraphenylethylene-Amplified Electrochemiluminescence by Regulating π-π Interaction.

The electrochemiluminescence (ECL) effectiveness of the tris(bipyridine) ruthenium(II) (Ru(bpy)) system is hampered by aggregation-caused quenching (ACQ) in optoelectronic systems as a result of π-π accumulation of the aromatic ring structure. In this work, a negatively charged tetraphenylvinyl molecule (TPE-2SONa, TPE-4SONa) was synthesized to modify the electrode interface, and the π-π accumulation between Ru(bpy) molecules was transformed into the π-π interaction between Ru(bpy) and TPE molecules. Interestingly, the ECL signal intensity of the Ru(bpy)-tripropylamine (TPA) system in the presence of TPE-2SONa was increased by about 15 times due to the π-π action and electrostatic action.

Liposome-assisted chemical redox cycling strategy for advanced signal amplification: A proof-of-concept toward sensitive electrochemiluminescence immunoassay.

This work presents a novel signal amplification strategy for electrochemiluminescence (ECL) biosensor based on liposome-assisted chemical redox cycling for in situ formation of Au nanoparticles (Au NPs) on TiO nanotubes (TiO NTs) electrode. The system was exemplified by ascorbic acid (AA)-loaded liposome, the redox cycling of AA utilizing tris (2-carboxyethyl) phosphine (TCEP) as reductant, and the use of Au nanoclusters (Au NCs)/TiO NTs as working electrode to implement the ECL detection of prostate specific antigen (PSA). Specifically, the AA-loaded liposomes were used as tags to label the captured PSA through a sandwich immunoreaction.

Dual-wavelength electrochemiluminescence ratiometry for hydrogen sulfide detection based on Cd-doped g-CN nanosheets.

Herein, a novel and facile dual-wavelength ratiometric electrochemiluminescence-resonance energy transfer (ECL-RET) sensor for hydrogen sulfide (HS) detection was constructed based on the interaction between S and Cd-doped g-CN nanosheets (NSs). Cd-doped g-CN NSs exhibited a strong ECL emission at 435 nm. In the presence of HS, CdS was formed on g-CN NSs by the adsorption of S and Cd, generating another ECL emission at 515 nm.

Liposome-assisted enzyme catalysis: toward signal amplification for sensitive split-type electrochemiluminescence immunoassay.

Developing an efficient signal amplification strategy is very important to improve the sensitivity of bioanalysis. In this paper, a liposome-assisted enzyme catalysis signal amplification strategy was developed for electrochemiluminescence (ECL) immunoassay of prostate specific antigen (PSA) in a split-type mode. The sandwich immunoreaction occurred in a 96-well plate, and glucose oxidase (GOx) encapsulated and antibody-modified liposomes were used as labels.

A novel chemiluminescence imaging immunosensor for prostate specific antigen detection based on a multiple signal amplification strategy.

A novel chemiluminescence (CL) imaging platform was constructed for prostate specific antigen (PSA) detection in a multiple signal amplifying manner. To construct the platform, the primary antibody for PSA was firstly immobilized on a O-ring area of a glass slide for recognizing the PSA. The horseradish peroxidase (HRP) and the secondary antibody of PSA (Ab) functionalized Au NPs (HRP-Au NPs-Ab) were modified on the platform through immunoreaction between PSA and Ab.