Cinnamaldehyde promotes diabetic wound healing via synergetic effects of AGE/RAGE-mediated macrophage polarization affecting fibroblast activation and angiogenesis, and Nrf2-dependent antioxidants.

Diabetic foot ulcer (DFU), a serious complication of diabetes mellitus (DM), is characterized by delayed wound healing and is a major cause of nontraumatic amputation. This study investigated cinnamaldehyde's regulatory effect on DFU and its underlying mechanisms. A DFU model was established in BALB/c mice using streptozotocin (STZ); mice received cinnamaldehyde (100 mg/kg, intraperitoneally).

Interactions between plants and bacterial communities for phytoremediation of petroleum-contaminated soil.

Plants can stimulate the microbes to degrade ubiquitous petroleum hydrocarbons (PHCs), which has prompted a novel view on rhizoremediation. In the present study, the degradation rate of PHCs was investigated and 16S rRNA gene analysis was performed to investigate the PHC-degrading bacteria in petroleum-contaminated soil with different plants. Mirabilis jalapa (M.