Predictive Value of Combining Padua Score with D-Dimer for Deep Vein Thrombosis in Acute Ischemic Stroke Patients with Alteplase.

Background: This study aimed to evaluate the predictive value of combining the Padua score with D-dimer levels for identifying lower extremity deep vein thrombosis (DVT) in acute ischemic stroke (AIS) patients undergoing intravenous thrombolysis with alteplase.

Methods: This retrospective study analyzed clinical data from 632 AIS patients who received alteplase treatment at our hospital between September 2019 and October 2023. After applying strict inclusion and exclusion criteria, a total of 172 patients were included in the analysis: 35 patients in the DVT group and 137 patients in the non-DVT group.

44,X,der(21;22)(q10;q10)[43]/45,XX,der(21;22)(q10;q10)[27] a Case Study of Mosaicism with Menstrual Disorders.

Background: Turner syndrome (TS), also known as congenital ovarian hypoplasia, is one of the most common sex chromosome diseases in women. It is caused by the complete or partial deletion or structural change of one X chromosome in all or part of somatic cells. A rare case of karyotype Turner syndrome is reported.

Catechol-facilitated Sn transport enables ultrahigh utilization rate of aqueous metallic tin anodes.

Catechol, a multifunctional electrolyte additive leveraging p-π conjugation, is proposed to regulate Sn solvation and facilitate Sn transport. This synergy enables highly reversible plating/stripping of the Sn anode at ultrahigh utilization rates.

Investigating the Effects of Different n-6 Polyunsaturated Fatty Acid Ratios on Ferroptosis in IPEC-J2 Cells.

Dietary n-6 and n-3 polyunsaturated fatty acid (PUFA) balance critically modulates various physiological processes, including inflammation and cell death. This study investigated the effects of different n-6 PUFA ratios (1:1, 5:1, 10:1, 20:1) on ferroptosis in porcine IPEC-J2 intestinal epithelial cells. Cells treated with varying PUFA ratios showed a significant reduction in cell viability, which was alleviated by the ferroptosis inhibitor ferrostatin-1 (fer-1).

Adjunctive Doxazosin before Ureterolithotripsy to Improve Successful Access Rate: A Retrospective Analysis.

Background: Ureteroscopic lithotripsy using a semi-rigid ureteroscope is the standard treatment for urinary stones. Doxazosin-an alpha-1 adrenergic receptor blocker-relaxes ureteral smooth muscles, reducing peristalsis and contraction frequency. This study aimed to evaluate the efficacy and safety of adjunctive doxazosin before semi-rigid ureteroscopy and retrograde intrarenal surgery (RIRS) for urinary stones.