Publications by authors named "Xuyan Sun"
The associations between oxidative stress and epilepsy: a bidirectional two-sample Mendelian randomization study.
Acta Epileptol
December 2024
Background: Studies on the association between oxidative stress and epilepsy have yielded varied results. In this study, we aimed to investigate the causal relationship between oxidative stress markers and epilepsy.
Methods: A bidirectional two-sample Mendelian randomization (MR) study was performed based on publicly available statistics from genome-wide association studies.
Article Synopsis
- - Dermal fibroblasts are essential for skin wound healing, but in diabetic foot ulcers, their migration and proliferation are hindered by harmful substances and inflammation.
- - A new drug delivery system using magnetic gelatin-hesperidin microrobots was created to enhance fibroblast activity while addressing the issues caused by high glucose levels.
- - These microrobots showed fast, controllable movement (up to 9.237 μm/s), and effectively released about 78% of the drug in 30 minutes, resulting in improved fibroblast proliferation and migration, making it a promising solution for diabetic wound healing.
As nanotechnology develops in the fields of mechanical engineering, electrical engineering, information and communication, and medical care, it has shown great promises. In recent years, medical nanorobots have made significant progress in terms of the selection of materials, fabrication methods, driving force sources, and clinical applications, such as nanomedicine. It involves bypassing biological tissues and delivering drugs directly to lesions and target cells using nanorobots, thus increasing concentration.
View Article and Find Full Text PDFCyclin-dependent kinase-like 5 (CDKL5) is a gene encoding a serine/threonine kinase that possesses an N-terminal catalytic domain and a large C-terminal domain and is located on the short arm of the X-chromosome at position 22 (Xp22). CDKL5 regulates neuronal migration, axonal growth, dendritic morphogenesis, and synaptic development and affects synaptic function. Pathogenic variants include deletions, truncations, splice variants, and missense variants.
View Article and Find Full Text PDFEfficacy of complete decongestive therapy and manual lymphatic drainage on treatment-related lymphedema in breast cancer.
Int J Radiat Oncol Biol Phys
March 2007
Objective: To evaluate the results of combined decongestive therapy and manual lymphatic drainage in patients with breast cancer-related lymphedema.
Methods And Materials: The data from 250 patients were reviewed. The pre- and posttreatment volumetric measurements were compared, and the correlation with age, body mass index, and type of surgery, chemotherapy, and radiotherapy was determined.