Publications by authors named "Xiongxiang Liu"
Tegoprazan-based versus esomeprazole-based triple therapy plus bismuth for first-line Helicobacter pylori eradication: A nationwide, multicenter, double-blind, double-dummy, randomized controlled trial.
Chin Med J (Engl)
August 2025
Background: Although triple therapy plus bismuth (TTPB), comprising a proton pump inhibitor (PPI), two antibiotics, and bismuth, is widely used to eradicate Helicobacter pylori (H. pylori), eradication rates have been suboptimal. Potassium-competitive acid blockers (P-CABs) offer stronger and more stable gastric acid inhibition compared to PPIs.
View Article and Find Full Text PDFSolamargine inhibits gastric cancer progression via inactivation of STAT3/PD‑L1 signaling.
Mol Med Rep
February 2025
Article Synopsis
- Gastric cancer has a high global mortality rate (70%) and involves immune checkpoints like PD-1 and PD-L1, which are important in its progression.
- Solamargine, derived from traditional Chinese medicine, shows potential in suppressing various cancers, but its specific impact on PD-L1 in gastric cancer was unclear.
- The study found that solamargine inhibits gastric cancer cell growth and metastasis by downregulating STAT3 signaling and reducing PD-L1 expression, suggesting it could be a promising treatment strategy for gastric cancer.
Background: In endoscopic nasobiliary drainage (ENBD), it is complicated to reposition the catheter from the mouth to nostril. We developed a new technique using an 1-mL syringe tube combined with guide-wire when repositioning an ENBD tube from mouth to nose. The aim of this study was to verify its utility.
View Article and Find Full Text PDF[Safety and efficacy of carbon dioxide insufflation during colonoscopy].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2009
Objective: To assess the safety and efficacy of carbon dioxide (CO(2)) in colonoscopy examination.
Methods: We randomized 349 patients to undergo colonoscopy with insufflation of air (n=175) or CO(2) (n=174). At colonoscopy, p (ET CO(2)) was observed at 4 time points: before the exam, arrived caecum, back rectum, and after the exam.