Art education plays a vital role in preserving cultural heritage and promoting sustainable development. However, growing curricular complexity and abstraction present challenges to student satisfaction, a key metric in educational sustainability. This study investigates how perceived content complexity and modality structure affect student satisfaction in art-related programs, drawing on Construal Level Theory (CLT) to explain the psychological mechanisms involved.
View Article and Find Full Text PDFThis study explores how employee-AI collaboration can promote employees' proactive behavior by reducing their workload, and examines the mediating role of workload and the moderating effect of AI literacy. Based on a survey of employees across multiple industries, the study finds that employee-AI collaboration significantly reduces employees' workload, which in turn encourages more proactive behavior. In this process, workload serves as a central mediating mechanism, as it helps alleviate task pressure and frees up cognitive resources, enabling employees to take on additional responsibilities and put forward innovative suggestions.
View Article and Find Full Text PDFLong non-coding RNAs (LncRNAs) could regulate chemoresistance through sponging microRNAs (miRNAs) and sequestering RNA binding proteins. However, the mechanism of lncRNAs in rituximab resistance in diffuse large B-cell lymphoma (DLBCL) is largely unknown. Here, we investigated the functions and molecular mechanisms of lncRNA CHROMR in DLBCL tumorigenesis and chemoresistance.
View Article and Find Full Text PDFBackground: As a three-dimensional network involving glycosaminoglycans (GAGs), proteoglycans (PGs) and other glycoproteins, the role of extracellular matrix (ECM) in tumorigenesis is well revealed. Abnormal glycosylation in liver cancer is correlated with tumorigenesis and chemoresistance. However, the role of galactosyltransferase in HCC (hepatocellular carcinoma) is largely unknown.
View Article and Find Full Text PDFLung cancer is the leading cause of cancer-related deaths worldwide. Combination of drugs targeting independent signaling pathways would effectively block the proliferation of cancer cells with lower concentrations and stronger synergy effects. Dasatinib, a multi-targeted protein tyrosine kinase inhibitor targeting BCR-ABL and kinases of SRC family, has been successfully applied in the treatment of chronic myeloid leukemia (CML).
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