Publications by authors named "Xin-Chen Li"
Global burden of viral infectious diseases of poverty based on Global Burden of Diseases Study 2021.
Infect Dis Poverty
October 2024
Article Synopsis
- Viral infectious diseases of poverty (vIDPs), such as COVID-19, HIV/AIDS, and others, greatly impact global health but lack comprehensive burden data; this study aims to quantify their effects using 2021 Global Burden of Diseases data.
- The analysis covers incidence, mortality, and disability-adjusted life years (DALYs) across 204 countries between 1990 and 2021, revealing that vIDPs led to approximately 8.7 million deaths and 259.2 million DALYs in 2021.
- Notably, COVID-19 accounted for the majority of these deaths (around 7.9 million), while acute hepatitis and HIV/AIDS showed high incidence and prevalence rates, and vID
Article Synopsis
- The One Health (OH) approach aims to control zoonotic events but lacks systematic assessment tools; this study applied the Global OH Index (GOHI) specifically for zoonoses.
- By using fuzzy analytic hierarchy process and fuzzy comparison matrix, the study evaluated 160 countries based on five key indicators to determine their OH performance regarding zoonoses.
- Results showed significant variations in GOHI-Zoonoses scores linked to factors like economics and environmental conditions, indicating areas for improvement in global strategies to enhance health across humans, animals, and the environment.
The rapid acceleration of global warming has led to an increased burden of high temperature-related diseases (HTDs), highlighting the need for advanced evidence-based management strategies. We have developed a conceptual framework aimed at alleviating the global burden of HTDs, grounded in the One Health concept. This framework refines the impact pathway and establishes systematic data-driven models to inform the adoption of evidence-based decision-making, tailored to distinct contexts.
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- The One Health approach is about keeping humans, animals, and the environment healthy together, and it's become more important because of issues like climate change and disease outbreaks.
- In China, while they're doing well in food security and managing drug resistance, they struggle more with climate change compared to other countries.
- Experts suggest that China needs a better plan to turn policies into real actions, and they should work together with different people and cultures to make this happen.
Tackling global health security by building an academic community for One Health action.
Infect Dis Poverty
August 2023
Background: One Health approach is crucial to tackling complex global public health threats at the interface of humans, animals, and the environment. As outlined in the One Health Joint Plan of Action, the international One Health community includes stakeholders from different sectors. Supported by the Bill & Melinda Gates Foundation, an academic community for One Health action has been proposed with the aim of promoting the understanding and real-world implementation of One Health approach and contribution towards the Sustainable Development Goals for a healthy planet.
View Article and Find Full Text PDFAntifungal and Antibiofilm In Vitro Activities of Ursolic Acid on Cryptococcus neoformans.
Curr Microbiol
August 2022
Ursolic acid (UA) exists in a variety of medicinal plants. UA exhibits antimicrobial activity against several microorganisms; however, little is known regarding the potential antifungal effect of UA on Cryptococcus neoformans (C. neoformans).
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