Implications for agricultural sustainability: predicting the global distribution of under current and future climate scenarios.

Introduction: A rapidly growing population and ongoing urbanization continue to strain agriculture's capacity to maintain a stable food supply, both through direct impacts such as land reclamation and indirect effects driven by accelerating climate change. One of the major consequences of climate change is the shifting geographic range of infectious plant pathogens, particularly , the causative agent of bacterial wilt. This pathogen poses a significant threat to several economically important crops including tomatoes, bananas, eggplants, and tobacco.

drug design and biological evaluation of coumarin-pyrimidine co-drug derivatives as diabetic inhibitors: expanding a multi-algorithm approach with the integration of machine learning in pharmaceutical research.

Optimization of hit compounds was carried out using the density functional theory. We introduce the coumarin-based co-drug by linkages (amide and oxime) of coumarins with pyrimidines to improve the pharmacokinetic activity of coumarin owing to the synergic effect of both collectively. Pharmacokinetic studies, including drug likeness, were performed using SWISSADMET, and toxicity was identified using a web-based server.

Deciphering maize resistance to late wilt disease caused by : agronomic, anatomical, molecular, and genotypic insights.

Introduction: , the causal agent of late wilt disease (LWD), poses a significant threat to maize production by reducing grain yield and quality. Identifying and developing resistant genotypes adapted to different environments is essential for sustainable crop improvement.

Methods: Fifteen maize genotypes were evaluated for their response to LWD across three growing seasons at two experimental locations-Gemmeiza and Sids.

Impact of climate change on the potential global prevalence of (Tassi) Goid. under several climatological scenarios.

Introduction: Climate change forms one of the most dangerous problems that disturb the earth today. It not only devastates the environment but also affects the biodiversity of living organisms, including fungi. (Tassi) Goid.

Semi-synthesis and biological activities of heterocyclic compounds containing camphor.

Breast cancer and lung cancer are two of the most prevalent and deadly malignancies worldwide. Both cancers present significant challenges in terms of effective treatment and management, highlighting the urgent need for novel therapeutic strategies that can improve patient outcomes. This study focuses on the synthesis of novel heterocyclic compounds derived from the naturally formed camphor, aimed at evaluating their cytotoxicity.

Spectroscopic analysis of wild medicinal desert plants from wadi sanor (beni-suef), Egypt, and their antimicrobial and antioxidant activities.

Desert plants possess untapped potential for medicinal applications due to their rich phytochemical profiles. However, they need to be more explored. Thus, this study integrates advanced analytical, biochemical, and molecular techniques to investigate the phytochemical composition and biological activities (antimicrobial and antioxidant) of four desert plants (, and , collected from Wadi Sannor, Beni-Suef Governorate, Egypt, in March 2021.

Novel composite of nano zinc oxide and nano propolis as antibiotic for antibiotic-resistant bacteria: a promising approach.

This study proposes an innovative approach to combat the escalating threat of antibiotic resistance in bacteria by introducing a novel ZnO-propolis nanocomposite (ZnO-P NCs). The overuse of antibiotics, particularly during events like the COVID-19 pandemic, has intensified bacterial resistance, necessitating innovative solutions. The study employs a cost-effective and controllable biosynthesis method to produce ZnO nanoparticles (ZnO-NPs), with propolis extract crucially contributing to the reduction and stabilization of Zn ions.

Actinobacterium-Mediated Green Synthesis of CuO/Zn-Al LDH Nanocomposite Using sp. ISP-2 27: A Synergistic Study that Enhances Antimicrobial Activity.

Bacterial resistance to conventional antibiotics has created an urgent need to develop enhanced alternatives. Nanocomposites combined with promising antibacterial nanomaterials can show improved antimicrobial activity compared to that of their components. In this work, green synthesized CuO nanoparticles (NPs) supported on an anionic clay with a hydrotalcite-like structure such as Zn-Al layered double hydroxide (LDH) nanocomposite were investigated as antimicrobial agents.

Poly-Gamma-Glutamic Acid Nanopolymer Effect against Bacterial Biofilms: In Vitro and In Vivo Study.

In this study, a biodegradable poly-gamma-glutamic-acid nanopolymer (Ɣ-PGA NP) was investigated for its activity against clinical strains of Gram-positive ( and ) and Gram-negative ( and ), and reference strains of ATCC 6538, ATCC 19615 (Gram-positive), and Gram-negative ATCC 25922, and ATCC 13884 bacterial biofilms. The minimum inhibitory concentration (MIC) effect of Ɣ-PGA NP showed inhibitory effects of 0.2, 0.

Cross-sectional analysis of risk factors associated with in retail fish markets concerning methicillin-resistant and .

Introduction: and methicillin-resistant (MRSA) are potent bacterial pathogens posing major hazards to human health via consuming fish harboring these pathogens or by cross-contamination beyond the contaminated environment. The aim of this study was to determine risk variables associated with the presence of certain pathogenic bacteria from fish in retail markets in Egypt. The virulence genes of and were also studied.

Combatting Sugar Beet Root Rot: Strains' Efficacy against .

Sugar beet root rot disease triggered by f. sp. is a destructive disease and dramatically affects the production and quality of the sugar beet industry.

Copper oxide nanoparticles: an effective suppression tool against bacterial leaf blight of rice and its impacts on plants.

Background: To address the challenges of food security for the ever-increasing population, the emergence of nanotechnology provides an alternate technology of choice for the production of safer pesticides which serves as a substitute for conventional fertilizer. The antidrug resistance of Xanthomonas oryzae pv. oryzae (Xoo) and build-up of chemicals in the environment has made it necessary to find alternative safe techniques for effective disease management.

Controlling Multi-Drug-Resistant Traits of Obtained from Retail Poultry Shops Using Metal-Organic Framework (MOF) as a Novel Technique.

spp. is considered one of the most important causes of food-borne illness globally. Poultry and its products are usually incriminated in its spread.

A New Cu/Fe Layer Double Hydroxide Nanocomposite Exerts Anticancer Effects against PC-3 Cells by Inducing Cell Cycle Arrest and Apoptosis.

Prostate cancer treatment poses significant challenges due to its varying aggressiveness, potential for metastasis, and the complexity of treatment options. Balancing the effectiveness of therapies, minimizing side effects, and personalizing treatment strategies are ongoing challenges in managing this disease. Significant advances in the use of nanotechnology for the treatment of prostate cancer with high specificity, sensitivity, and efficacy have recently been made.

Modulation of mi-RNA25/Ox-LDL/NOX4 signaling pathway by polyphenolic compound Hydroxytyrosol as a new avenue to alleviate cisplatin-induced acute kidney injury, a mechanistic study in rats.

Acute kidney injury (AKI) caused by Cis is considered one of the most severe adverse effects, which restricts its use and efficacy. This study seeks to examine the potential reno-protective impact of phenolic compound Hydroxytyrosol (HT) against Cis-induced AKI and the possible involvement of the mi-RNA25/Ox-LDL/NOX4 pathway elucidating the probable implicated molecular mechanisms. Forty rats were placed into 5 groups.

Green Synthesis of Zinc Oxide Nanoparticles Using Extract and Its Antibacterial Activity.

Excessive use of antimicrobial medications including antibiotics has led to the emerging menace of antimicrobial resistance, which, as per the World Health Organization (WHO), is among the top ten public health threats facing humanity, globally. This necessitates that innovative technologies be sought that can aid in the elimination of pathogens and hamper the spread of infections. Zinc oxide (ZnO) has multifunctionality owing to its extraordinary physico-chemical properties and functionality in a range of applications.

Bio-functionalized nickel-silica nanoparticles suppress bacterial leaf blight disease in rice ( L.).

Introduction: Bacterial leaf blight (BLB) caused by pv () is one of the most devastative diseases that threatens rice plants worldwide. Biosynthesized nanoparticle (NP) composite compounds have attracted attention as environmentally safe materials that possess antibacterial activity that could be used in managing plant diseases.

Methods: During this study, a nanocomposite of two important elements, nickel and silicon, was biosynthesized using extraction of saffron stigmas ( L.

Bacteriophage-mediated biosynthesis of MnONPs and MgONPs and their role in the protection of plants from bacterial pathogens.

Introduction: oryzae pv. (Xoo) is the plant pathogen of Bacterial Leaf Blight (BLB), which causes yield loss in rice.

Methods: In this study, the lysate of Xoo bacteriophage X3 was used to mediate the bio-synthesis of MgO and MnO.

Alkalihalobacillus deserti sp. nov., Isolated from the Saline-Alkaline Soil.

A bacterial strain, designated TRPH29, was isolated from saline-alkaline soil, collected from the southern edge of the Gurbantunggut desert, Xinjiang, People's Republic of China. The isolate was Gram-staining positive, facultatively anaerobic, straight rods. Growth occurred at 15-40 °C (optimum, 28 °C), pH 8.

Potential Application of Innovative / Sodium Alginate Composite Beads as Eco-Friendly and Sustainable Adsorbents for Alizarin Red S Dye: Isotherms and Kinetics Models.

Fungi were used as one of the most common bioremediation methods. From this perspective, our study highlights the optimization of Alizarin Red S (ARS) dye adsorption performance for the sodium alginate (SA) by using the fungus () to form a composite bead and the possibility of its reusability. This was accomplished by mixing SA with different ratios of biomass powder of including 0%, 10%, 20%, 30%, and 40%, to form composite beads of /SA-0%, /SA-10%, /SA-20%, /SA-30%, and /SA-40%, respectively.

Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics approaches.

There has been progressive improvement in immunoinformatics approaches for epitope-based peptide design. Computational-based immune-informatics approaches were applied to identify the epitopes of SARS-CoV-2 to develop vaccines. The accessibility of the SARS-CoV-2 protein surface was analyzed, and hexa-peptide sequences (KTPKYK) were observed having a maximum score of 8.