Publications by authors named "Vishal Chaudhary"

Considering the complexities of electronics waste management to meet the requirements of digital-age technologies, this article underscores the pressing need for eco-friendly, economical, and sustainable engineering solutions. Here, it uniquely focuses on bacteriogenic metallic and semiconducting nano-systems as a promising yet underexplored solution for sustainable materials innovation. Unlike conventional green nanofabrication methods involving plants or eukaryotic microbes, bacteria possess numerous merits for fabrication, including ease of cultivation, a wide spectrum of genera, abundance, prompt cell division efficacy, genetic elasticity, and high bio-reduction/oxidation efficacy that make them highly adaptable platforms for engineered nanostructures.

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The exponential growth of the global population in the digital era has accelerated urbanization and industrialization, leading to severe complex water pollution from the discharge of toxic dyes into aquatic ecosystems. Two dimensional (2D) MXene-based nano-adsorbents recently emerged as promising candidates for developing sustainable wastewater remediation technologies due to their tunable physicochemical properties, including a high negative zeta potential, a large specific surface area, exceptional adsorption capacity, superior electrical and thermal conductivity, hydrophilicity, and rich surface chemistry. Strategic optimization approaches for MXenes, encompassing interlayer spacing modification, surface engineering, stoichiometric tuning, morphological control, bandgap engineering, membrane fabrication, hybridization, and functionalization, have significantly enhanced their adsorptive performance and dye removal efficiency for real-time wastewater treatment applications.

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Polycystic ovarian syndrome (PCOS) is an endocrine disease characterized by hormonal imbalances, metabolic inefficiency, and infertility problems. Furthermore, anti-Müllerian hormone (AMH), testosterone, and insulin are PCOS biomarkers that need to be detected accurately for early diagnosis and treatment. A narrative review discusses current improvements in nanomaterial-enhanced biosensors that detect biomarkers with high sensitivity and specificity.

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Monitoring cancer therapy is difficult because of restricted imaging depth, inadequate molecular specificity, and delayed response evaluation. Moreover, conventional imaging techniques fail to provide high-resolution, real-time views of the dynamic tumor microenvironment during therapy. Among emerging technologies, nanophotonic photoacoustic biosensors have gained prominence as multifunctional platforms that enable real-time, non-invasive imaging and dynamic monitoring of cancer therapy.

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Bismuth stannate (BiSnO) has emerged as a promising compound for heterostructure applications due to its outstanding photocatalytic, structural, and optical properties. As a pyrochlore-type semiconducting material, BiSnO demonstrates a suitable bandgap, strong visible-light absorption, and high chemical stability, making it attractive for environmental remediation. Heterostructures based on BiSnO have gained significant attention because of their enhanced charge carrier separation efficiency, improved charged carrier mobility, and synergistic effects that boost photocatalytic performance.

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Nano-optical biosensors have emerged as transformative tools in healthcare and clinical research, offering rapid, portable, and specific diagnostic solutions. This review critically analyzes the recent advancements, translational challenges, and sustainable approaches in nano-optical biosensor implementation for biomedical applications. We explore the integration of innovative nanomaterials, microelectronics, and molecular biology techniques that have significantly enhanced biosensor sensitivity and specificity, enabling detection of biomarkers ranging from cancer indicators to cardiovascular markers.

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Semiconducting and metallic nanomaterials are essential building blocks for developing modern-age technologies, and their demand is expanding exponentially with a growing population. However, their processing impacts the ecosystem and requires urgently sustainable solutions. This perspective underlines the emergence of microbe-mediated (bacteria, yeast, fungi, microalgae, viruses, cyanobacteria) green nanomaterials, including metal-based, carbon-based, organic and hybrid nanomaterials, with technical challenges of scalability, stability and cytotoxicity restricting their transition from lab-to-market.

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Neuroprobes that use nanostructured photonic interfaces are capable of multimodal sensing, stimulation, and imaging with unprecedented spatio-temporal resolution. In addition to electrical recording, optogenetic modulation, high-resolution optical imaging, and molecular sensing, these advanced probes combine nanophotonic waveguides, optical transducers, nanostructured electrodes, and biochemical sensors. The potential of this technology lies in unraveling the mysteries of neural coding principles, mapping functional connectivity in complex brain circuits, and developing new therapeutic interventions for neurological disorders.

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Lung cancer remains a global health concern, demanding the development of noninvasive, prompt, selective, and point-of-care diagnostic tools. Correspondingly, breath analysis using nanobiosensors has emerged as a promising noninvasive nose-on-chip technique for the early detection of lung cancer through monitoring diversified biomarkers such as volatile organic compounds/gases in exhaled breath. This comprehensive review summarizes the state-of-the-art breath-based lung cancer diagnosis employing chemiresistive-module nanobiosensors supported by theoretical findings.

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This review explores the crystallographic versatility of niobium pentoxide (NbO) at the nanoscale, showcasing enhanced catalytic efficiency for cutting-edge sustainable energy and environmental applications. The synthesis strategies explored encompass defect engineering, doping engineering, s-scheme formation, and heterojunction engineering to fine-tune the physicochemical attributes of diverse dimensional (0-D, 1-D, 2-D, and 3-D) NbO nanosystems as per targeted application. In addressing escalating environmental challenges, NbO emerges as a semiconductor photocatalyst with transformative potential, spanning applications from dye degradation to antibiotic and metal removal.

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Article Synopsis
  • Antimicrobial resistance (AMR) is a growing global health threat caused by the misuse of antibiotics, highlighting the need for innovative and sustainable solutions.* -
  • Bio-nanomaterials, made from eco-friendly precursors like biowaste and plant extracts, offer a sustainable way to combat AMR by targeting pathogens and enhancing the effectiveness of existing antibiotics.* -
  • This review discusses the potential uses of bio-nanomaterials in various health applications, their advantages in antimicrobial therapy, and the regulatory challenges they face, promoting a more sustainable approach to healthcare.*
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Achieving sustainable future energy goals includes enhancing renewable energy production, optimizing daily energy consumption using feedback loops and minimizing/monitoring contributions to atmospheric carbon dioxide (CO). Developing economic next-generation COsensors enables local monitoring of industrial COemissions, aiding energy management and climate monitoring. This study elucidates the efficacy of COchemiresistor based on indium oxide (InO) micro cubes with spilled-over nanoparticles.

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Antimicrobial resistance (AMR) poses a critical global One Health concern, ensuing from unintentional and continuous exposure to antibiotics, as well as challenges in accurate contagion diagnostics. Addressing AMR requires a strategic approach that emphasizes early stage prevention through screening in clinical, environmental, farming, and livestock settings to identify nonvulnerable antimicrobial agents and the associated genes. Conventional AMR diagnostics, like antibiotic susceptibility testing, possess drawbacks, including high costs, time-consuming processes, and significant manpower requirements, underscoring the need for intelligent, prompt, and on-site diagnostic techniques.

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Hazardous heavy metal (HM) pollution constitutes a pervasive global challenge, posing substantial risks to ecosystems and human health. The exigency for expeditious detection, meticulous monitoring, and efficacious remediation of HM within ecosystems is indisputable. Soil contamination, stemming from a myriad of anthropogenic activities, emerges as a principal conduit for HM ingress into the food chain.

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Clean room facilities are becoming more popular in both academic and industry settings, including low-and middle-income countries. This has led to an increased demand for cost-effective gas sensors to monitor air quality. Here we have developed a gas sensor using CoNiOnanoparticles through combustion method.

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Rapid technological advancements have created opportunities for new solutions in various industries, including healthcare. One exciting new direction in this field of innovation is the combination of skin-based technologies and augmented reality (AR). These dermatological devices allow for the continuous and non-invasive measurement of vital signs and biomarkers, enabling the real-time diagnosis of anomalies, which have applications in telemedicine, oncology, dermatology, and early diagnostics.

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Herein, we have reported a photocatalytic BiOI, protonated g-CN heterojunction with directional charge transfer channels provided by tea waste biochar to achieve effective e/h pair isolation for the improved degradation of Methylene blue (MB) and Doxycycline hydrochloride (DCHCl). An S-scheme heterojunction was fabricated via the novel method that combined hydrothermal and ultrasonic dispersion, followed by an electrostatic self-assembly route. The as-fabricated BiOI/protonated g-CN/Tea waste biochar heterojunction formed a strong contact at the interface, as supported by the electron microscopic results.

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Diversified nanosystems with tunable physicochemical attributes have emerged as potential solution to globally devastating cancer by offering novel possibilities for improving the techniques of cancer detection, imaging, therapies, diagnosis, drug delivery and treatment. Drug delivery systems based on nanoparticles (NPs) with ability of crossing different biological barriers are becoming increasingly popular. Besides, NPs are utilized in pharmaceutical sciences to mitigate the toxicity of conventional cancer therapeutics.

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Comprehending the morphological disparities between SARS-CoV-2 and SARS-CoV viruses can shed light on the underlying mechanisms of infection and facilitate the development of effective diagnostic tools and treatments. Hence, this study aimed to conduct a comprehensive analysis and comparative assessment of the morphology of SARS-CoV-2 and SARS-CoV using transmission electron microscopy (TEM) images. The dataset encompassed 519 isolated SARS-CoV-2 images obtained from patients in Italy (INMI) and 248 isolated SARS-CoV images from patients in Germany (Frankfurt).

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The mutating SARS-CoV-2 necessitates gauging the role of airborne particulate matter in the COVID-19 outbreak for designing area-specific regulation modalities based on the environmental state-of-affair. To scheme the protocols, the hotspots of air pollutants such as PM, PM, NH, NO, NO, SO, and and environmental factors including relative humidity (RH), and temperature, along with COVID-19 cases and mortality from January 2020 till December 2020 from 29 different ground monitoring stations spanning Delhi, are mapped. Spearman correlation coefficients show a positive relationship between SARS-COV-2 with particulate matter (PM with r > 0.

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The ever-increasing demand for food from the growing population has augmented the consumption of fertilizers in global agricultural practices. However, the excessive usage of chemical fertilizers with poor efficacy is drastically deteriorating ecosystem health through the degradation of soil fertility by diminishing soil microflora, environment contamination, and human health by inducing chemical remnants to the food chain. These challenges have been addressed by the integration of nanotechnological and biotechnological approaches resulting in nano-enabled biogenic fertilizers (NBF), which have revolutionized agriculture sector and food production.

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Thank you so much for forwarding the critical analysis the author (VK) conducted on our recently published modelling study 'A Cost-Effectiveness Analysis of Pre-Exposure Prophylaxis to Avert Rabies Deaths in School-Aged Children in India' in your reputed journal [...

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Metal/metal oxide nano systems (M-NSs) of tunable and manipulative properties are emerging suitable for cancer management via immunity development, early-stage diagnosis, nanotherapeutics, and targeted drug delivery systems. However, noticeable toxicity, off-targeted actions, lacking biocompatibility, and being expensive limit their acceptability. Moreover, involving high energy (top-down routes) and hazardous chemicals (bottom-up chemical routes) is altering human cycle.

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A nano-enabled low-trace monitoring system for acetone has the potential to revolutionize breath omics-based non-invasive diagnosis of human diabetes and environmental monitoring technologies. This unprecedented study presents the state-of-the-art facile and economic template-assisted hydrothermal route to fabricate novel CuMoO nanorods for room temperature breath and airborne acetone detection. Physicochemical attribute analysis reveals the formation of crystalline CuMoO nanorods with diameters ranging from 90 to 150 nm, and an optical band gap of approximately 3.

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Constantly mutating SARS-CoV-2 is a global concern resulting in COVID-19 infectious waves from time to time in different regions, challenging present-day diagnostics and therapeutics. Early-stage point-of-care diagnostic (POC) biosensors are a crucial vector for the timely management of morbidity and mortalities caused due to COVID-19. The state-of-the-art SARS-CoV-2 biosensors depend upon developing a single platform for its diverse variants/biomarkers, enabling precise detection and monitoring.

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